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HRQOL is significantly adversely affected in BD patients. Additionally, the presence of comorbid conditions highly prevalent in BD further decreases HRQOL for these patients. In spite of these factors, this review offers renewed hope as several treatment regimens correlate with higher post-intervention HRQOL scores.

There are specific and identifiable impacts of childhood cancer on patients' HRQoL that are significant and complex across the span of the illness. There is a need for continued research in many areas related to this population, especially related to those with terminal illness in order to improve patient care.

Key content Over the last two to three decades there has been a 15–25% increase in many countries in the number of women giving birth to large infants. Rates of shoulder dystocia and caesarean birth rise substantially at 4000 g and again at 4500 g. There is an increase in maternal and neonatal morbidity associated with fetal macrosomia. Serial measurement of fundal height adjusted for maternal physiological variables substantially improves antenatal detection. Sonographic assessment of fetal weight is frequently inaccurate. Induction of labour for suspected macrosomia in non‐diabetic women has not been shown to reduce the risk of caesarean section, instrumental delivery or perinatal morbidity. Learning objectives To identify the risks associated with fetal macrosomia and to be aware of the long‐term implications. To understand the limitations of predictive tools. To be able to take an informed approach to managing the macrosomic fetus. Ethical issues To what extent should the fear of medico‐legal action influence obstetricians' management of suspected fetal macrosomia? What advice should clinicians give women regarding modes of delivery? Please cite this article as: Aye SS, Miller V, Saxena S, Farhan M. Management of large‐for‐gestational‐age pregnancy in non‐diabetic women. The Obstetrician & Gynaecologist 2010;12:250–256.

Adolescence is a transitional period and an important stage in an individual's life. Adolescents are at risk of adverse reproductive health outcomes such as unplanned or unwanted pregnancy, unsafe abortions, maternal health complications, and sexually transmitted diseases (STDs) including HIV/AIDS. Previous studies indicate that adolescents whose parents talk to them about sex tend to be less sexually active and more likely to use an effective means of contraception. The objective of the study was to find out the level and content of communication between adolescents and their parents. Ease of communication, future intentions to discuss with parents and confidence in parents' knowledge of reproductive health were also examined. A cross sectional descriptive study using structured questionnaire was conducted among 91 adolescents (11-19 years old) in North Okkalapa Township of Yangon Division, Myanmar. The majority of the people there had little knowledge on pubertal changes and STDs, and moderate knowledge on contraception. Sixty three percent of adolescents communicated at least once with their parents on reproductive health within the last 6 months: 6.8% with fathers and 62.6% with mothers. Only 15.4% talked more than three times. Girls were more likely to communicate with mothers than boys (79% vs. 33%, P<0.001). The main topic of discussion among mother and girls is menstruation, and among mothers and boys, HIV/AIDS/STDs are mainly discussed. Regarding the ease of communication, only 15% felt comfortable talking with parents. Most of the adolescents (89%) had positive attitude towards communicating with their parents. The findings suggest the need to involve parents in existing adolescent reproductive health programs and design interventions focusing on parents to promote parent-adolescent communication. DOI: http://dx.doi.org/10.3329/seajph.v1i1.13219 South East Asia Journal of Public Health 2011:1:40-45