<p class="abstract"><strong>Background:</strong> Androgenetic alopecia is characterized by progressive hair loss and is recognized as having significant psychological effects on affected patients with a negative impact on QOL. Drug therapies specifically approved by FDA for treating androgenetic alopecia (AGA) are limited to minoxidil and finasteride. There are limited three arm studies comparing treatment modalities in AGA, hence we undertook this study to compare the 3 most common, affordable therapeutic modalities used currently in AGA and their effects.</p><p class="abstract"><strong>Methods:</strong> This is a prospective comparative parallel group interventional study. 90 subjects recruited into 3 groups, group A treated with minoxidil alone, group B with minoxidil and dermaroller and group C with minoxidil and platelet rich plasma (PRP).<strong></strong></p><p class="abstract"><strong>Results:</strong> At the end of 5 months 50% patients in group C showed moderate improvement which was found to be superior to the other treatment groups. On the basis of global photographs secondary efficacy analysis was done and all arms were found to have slight improvement. Dermoscopic analysis done at baseline and 5 months showed that group C showed maximum improvement. Pain was the most common side effect noted in group C while pruritus and seborrheic dermatitis was seen more in group A. </p><p class="abstract"><strong>Conclusions:</strong> Our study showed best results in patients treated with PRP and minoxidil. They have emerged as new non-surgical treatment modalities for AGA, with minimal side effects, good safety profile and patient satisfaction. There are limited three arm studies comparing the efficacy and side effect profile of these 3 modalities in AGA. </p><p> </p>
Faun tail nevus is a rarely reported congenital cutaneous marker of an underlying spine or spinal cord anomaly characterized by the presence of a hypertrichotic patch affecting the lumbosacral region since birth. In addition to spinal dysraphism, it also affects the psychosocial life of the suffering patient. Herein, we report two cases of faun tail nevus, one with associated diastematomyelia. In both cases, cosmetic improvement was achieved with triple-wavelength diode laser. This article aims to present this sparsely reported clinical entity and describe our experience in its management with diode laser.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.