Our study suggests that the severity of CTS strongly correlates with color Doppler sonography findings, and this technique may represent a reliable complementary tool in CTS examination.
The production of blood cells is affected by leukemia, a type of bone marrow cancer or blood cancer. Deoxyribonucleic acid (DNA) is related to immature cells, particularly white cells, and is damaged in various ways in this disease. When a radiologist is involved in diagnosing acute leukemia cells, the diagnosis is time consuming and needs to provide better accuracy. For this purpose, many types of research have been conducted for the automatic diagnosis of acute leukemia. However, these studies have low detection speed and accuracy. Machine learning and artificial intelligence techniques are now playing an essential role in medical sciences, particularly in detecting and classifying leukemic cells. These methods assist doctors in detecting diseases earlier, reducing their workload and the possibility of errors. This research aims to design a deep learning model with a customized architecture for detecting acute leukemia using images of lymphocytes and monocytes. This study presents a novel dataset containing images of Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). The new dataset has been created with the assistance of various experts to help the scientific community in its efforts to incorporate machine learning techniques into medical research. Increasing the scale of the dataset is achieved with a Generative Adversarial Network (GAN). The proposed CNN model based on the Tversky loss function includes six convolution layers, four dense layers, and a Softmax activation function for the classification of acute leukemia images. The proposed model achieved a 99% accuracy rate in diagnosing acute leukemia types, including ALL and AML. Compared to previous research, the proposed network provides a promising performance in terms of speed and accuracy; and based on the results, the proposed model can be used to assist doctors and specialists in practical applications.
A cancer diagnosis is one of the most difficult medical challenges. Leukemia is a type of cancer that affects the bone marrow and/or blood and accounts for approximately 8% of all cancers. Understanding the epidemiology and trends of leukemia is critical for planning. Specialists diagnose leukemia using morphological analysis, but there is a possibility of error in diagnosis. Since leukemia is so difficult to diagnose, intelligent methods of diagnosis are required. The primary goal of this study is to develop a novel method for extracting features hierarchically and accurately, in order to diagnose various types of acute leukemia. This method distinguishes between acute leukemia types, namely Acute Lymphocytic Leukemia (ALL) and Acute Myeloid Leukemia (AML), by distinguishing lymphocytes from monocytes. The images used in this study are obtained from the Shahid Ghazi Tabatabai Oncology Center in Tabriz. A type-II fuzzy deep network is designed for this purpose. The proposed model has an accuracy of 98.8% and an F1-score of 98.9%, respectively. The results show that the proposed method has a high diagnostic performance. Furthermore, the proposed method has the ability to generalize more satisfactorily and has a stronger learning performance than other methods.
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