The article reviews the literature on the classification of endothelial-epithelial dystrophy (EED) of the cornea. The description of endothelial structure, etiology and pathogenesis of the corneal EED are described. Based on own multiple observations and modern methods of corneal tissue imaging, a new modification of the EED classification by V.V. Volkov and M.M. Dronov was created and is presented in the article. This classification makes it possible to more accurately determine the etiopathogenesis of changes in corneal layers and to choose a most rational and effective treatment method. (For citation: Riks IA, Papanyan SS, Astakhov SYu, Novikov SA. Novel clinico-morphological classification of the corneal endothelial-epithelial dystrophy. Ophthalmology Journal. 2017;10(3):46-52. doi: 10.17816/OV10346-52).

Primary endothelial dystrophy of the cornea is a fairly common disease in people older than 50 years. Well-developed methods of conservative treatment, as a rule, do not lead to improvement or stabilization of the functional state of the cornea. The choice of tactics of surgical treatment from the existing variety of techniques is complicated. There are isolated reports of the restoration of corneal transparency after descemet membrane removal. The author's method of endothelial corneal dystrophy treatment addressed in this particular clinical case - a combination of isolated descemetorhexis and collagen cross-linking - resulted in impressive increase in visual acuity and significant improvement in objective criteria for the morpho-functional state of the cornea. (For citation: Astakhov SYu, Riks IA, Papayan SS, et al. About a new approach to surgical treatment of corneal endothelial dystrophy. Ophthalmology Journal. 2018;11(1):78-84. doi: 10.17816/OV11178-84).

The article presents a case of Urrets-Zavalia syndrome development in a patient after a subtotal penetra ting keratoplasty, carried out for corneal opacity. Since this syndrome was diagnosed in time, it was possible to avoid further complications and worsening of visual functions in 25-year-old patient.

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Relevance. Currently, all over the world, during cataract surgeries, a huge number of intraocular lenses (IOLs) made of different materials are implanted. Alongside with the development of modern IOL materials and designs, publications about their opacities appear. The nature and the localization of IOL opacities mainly depend on the properties of the material out of which the lens is made. Polymethyl methacrylate (PMMA) currently rarely used to manufacture IOLs, tends to cloud in the optical center due to structural breakdown, forming snowflake-like cracks. Opacities of acrylic IOLs depend on the degree of hydrophilic properties of the material. The deposition of crystalline deposits in the optical zone of hydrophilic acrylic lenses leads to a significant decrease in visual acuity and requires IOL explantation. There is a definite dependence of the occurrence of opacities in hydrophilic acryl on the patients concomitant diseases. In hydrophobic acrylic IOLs, vacuoles form, and glistenings occurs. Herewith, visual functions, as a rule, do not suffer. Purpose: to find out what structural changes in the IOL led to the need to remove them from pseudophakic eyes due to a decrease in visual acuity. Materials and methods. Four clouded IOLs made from different materials were examined. The lenses were studied using a SUPRA 55VP scanning electron microscope (Carl Zeiss, Germany) using a secondary electron detector. Element distribution maps on the surface and inside the lenses were collected using an X-max 80 mm2 energy dispersive X-ray analysis detector (Oxford Instruments, UK). Results. A hydrophilic lens with hydrophobic coating became cloudy 5 years after implantation. Hydroxyapatite crystals were found on all parts of the IOL along its surface. In a hydrophobic acrylic IOL, microvacuoles and cavities in the optical center were found using scanning electron microscopy. Two PMMA IOLs underwent self-destruction within 8 years after implantation. Chemical analysis of PMMA lenses did not reveal any inorganic compounds. Conclusion. One of the complications of IOL implantation is an impairment of their transparency. Factors associated with IOL material and manufacturing, as well as the patients comorbidities, can lead to lens opacification at various terms after surgery.