Listeriosis is a severe foodborne disease commonly caused by eating contaminated food with the Listeria species. A large variety of foods, especially dairy foods and ready-to-eat products, can support the growth of pathogens. Outbreaks of listeriosis have been related with milk, cheese, vegetable salads, and meat products, and fatality rates are typically around 20% due to listeriosis. The Centers for Disease Control and Prevention evaluates that 2500 infections and more than 500 deaths are related with listeriosis each year in the United States. A total 125 milk and dairy products were included in the study. Isolation and identification of this specie was done and then confirmed it by gram staining. Antimicrobial sensitivity was also checked. Prevalence of Listeria species were 16.8%, Listeria monocytogenes was 13.6%. Listeria monocytogenes was resistant against Ampicillin, Amoxicillin, Penicillin and sensitive Fosfomycin, Ciprofloxacin, Gentamycin. The results of this study showed the low prevalence of Listeria monocytogenes.

Antimicrobial agents are the most valuable means available for treating bacterial infections. Lincomycin and tetracycline are common brand having antibacterial activity. It is considered to be a cost-effective drugs because of its low cost, good activity against pathogenic anaerobic bacteria, favorable pharmacokinetic and pharmacodynamics. Antibiotic in the animal feed as growth promoters are primarily source of antibiotic resistance and stress factor for gut epithelium. Current studies will elaborate the advances in understanding toxicity induce by tetracycline and lincomycin on mucosal layer of gut of broiler. Following parameters such feed intake, weight gain and feed conversion ratio were studied on weekly basis which show FCR of the lincomycin group was greater as compared to tetracycline group and control group minimum FCR was found in tetracycline group. ND and IBD (New castle disease and Infectious bursal disease) titer was also affected.