Background Concerns regarding potential neurological complications of COVID-19 are being increasingly reported, primarily in small series. Larger studies have been limited by both geography and specialty. Comprehensive characterisation of clinical syndromes is crucial to allow rational selection and evaluation of potential therapies. The aim of this study was to investigate the breadth of complications of COVID-19 across the UK that affected the brain. Methods During the exponential phase of the pandemic, we developed an online network of secure rapid-response case report notification portals across the spectrum of major UK neuroscience bodies, comprising the Association of British Neurologists (ABN), the British Association of Stroke Physicians (BASP), and the Royal College of Psychiatrists (RCPsych), and representing neurology, stroke, psychiatry, and intensive care. Broad clinical syndromes associated with COVID-19 were classified as a cerebrovascular event (defined as an acute ischaemic, haemorrhagic, or thrombotic vascular event involving the brain parenchyma or subarachnoid space), altered mental status (defined as an acute alteration in personality, behaviour, cognition, or consciousness), peripheral neurology (defined as involving nerve roots, peripheral nerves, neuromuscular junction, or muscle), or other (with free text boxes for those not meeting these syndromic presentations). Physicians were encouraged to report cases prospectively and we permitted recent cases to be notified retrospectively when assigned a confirmed date of admission or initial clinical assessment, allowing identification of cases that occurred before notification portals were available. Data collected were compared with the geographical, demographic, and temporal presentation of overall cases of COVID-19 as reported by UK Government public health bodies.

AimsTo ensure close monitoring of physical health parameters when antipsychotics are prescribed and to liaise with primary care to ensure appropriate interventions are implemented.BackgroundAntipsychotics are the most frequently prescribed psychotropic medication for PwID. Treatment with antipsychotic agent is associated with cardio-metabolic risks such as obesity, diabetes, and dyslipidemia. A strong association is well documented between antipsychotic use and the risk of stroke in schizophrenia although the magnitude of this association has yet to be studied in PwID.PwID have an increased risk of premature death. Cardio-metabolic monitoring and appropriate intervention to this vulnerable cohort will improve the preventable cardio-metabolic multi-morbidity. The NICE guideline (CG11) recommends antipsychotic medication should only be initially prescribed and monitored by the secondary care professionals for at least 12 months. They also should work together with primary care to ensure appropriate interventions are arranged where necessary.MethodA retrospective audit was performed for 40 service users, taking antipsychotic medication. Quota sampling was used to identify 10 cases each from the caseload of 4 consultant psychiatrists, within the Intellectual Disability community setting, between September 2019 and October 2019.An audit tool was designed, in accordance with cardio-metabolic measures (smoking status, height, weight, Blood Pressure, HbA1c, Lipid profile), based on physical health CQUIN targets and the Lester adaptation tool. Collection of data was performed from electronic case records and electronic blood results service. The work was performed with the approval of local clinical audit team and analysed by using Microsoft Excel.ResultBaseline cardio-metabolic assessment was observed in over a half of the sample population (50–65%) whilst only less than 15% was noted at 3–6 months. Documentation Evaluation of physical health assessments for new admissions to the Oleaster during the first wave of COVID-19 on body weight and blood pressure was seen only in 15% and 2.5% of population respectively at 3–6 months. Collaboration with GP for annual health check was observed in 78–100% of population.Intriguingly, our finding indicates a significant improvement in all required compliance when nursing team is involved.ConclusionImproving physical healthcare is essential to reduce the cardio metabolic outcome in PwID taking antipsychotic medication. Better involvement of community nurses as well as availability of Sphygmomanometers at every outpatient clinic will determine the successful implementation of cardio metabolic monitoring and effective collaboration with primary care clinicians.Once the action plan is disseminated to the teams, the impact of change will be reassessed by a re-audit in one year's time.

To assess impacts of clear-cutting at a pure Acacia plantation on soil and water quality, a 7-year-old Acacia forest within the area of 2.5 ha in Hoa Binh province was selected to investigate at 2 stages: before and after clear-cutting. 03 standard plots (500 m2/plot) at 3 positions (downhill, mid-hill and top-hill) for determining forest characteristics, 30 sampling subplots (1 m2/plot) for monitoring forest covers and some soil properties. 15 of 30 subplots were used to measure infiltration; and 4 points along forest flow were chosen to take water sampling for assessing water quality. Main findings include: (1) Forest cover decreased within the removal of tree, reduction of understory vegetation cover, litter and biomass ranged from 10 to 20%; (2) Soil quality decreased by 8.35% dropped of porosity due to the rise of 8.57% in dry bulk density; (3) Soil nutrients: Organic matter, total Phosphorus and Nitrogen amount decreased at the proportion of 20.91%, 62.86% and 27.86% respectively after clear-cutting; (4) Total infiltration rate decreased after harvesting. The positions that had high infiltration rate before clear-cutting tended to infiltrate noticeably less (Downhill: reducing from 397.7 mm to 201.2 mm); (5) Soil erosion increased significantly after cutting and was remarkably higher in comparison with other research results due to the slope of researching area; (6) Most water quality indicators were at acceptable values, however, TSS and COD were 180-time and 5.6-time higher than water standard at B1 category (water for irrigation) according to QCVN 08:2015/BTNMT; (7) Some solutions suggested for sustainable management are (a) replacing production planted forest at researching site by protection forest or natural forest or (b) remaining commercial plantation forest but adjust management methods.

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