Background
Coronavirus disease 2019 (COVID-19) has led to a widespread morbidity and mortality. Limited data exists regarding the involvement of cardiovascular system in COVID-19 patients. We sought to evaluate the cardiovascular (CV) complications and its impact on outcomes in symptomatic COVID-19 patients.
Methods
This was a single center observational study among symptomatic COVID-19 patients. Data regarding clinical profile, laboratory investigations, CV complications, treatment and outcomes were collected. Cardiac biomarkers and 12 lead electrocardiograms were done in all while echocardiography was done in those with clinical indications for the same. Corrected QT-interval (QTc) at baseline and maximum value during hospitalization were computed.
Results
Of the 108 patients, majority of them were males with a mean age of 51.2 ± 17.7 years. Hypertension (38%) and diabetes (32.4%) were most prevalent co-morbidities. ECG findings included sinus tachycardia in 18 (16.9%), first degree AV block in 5 (4.6%), VT/VF in 2 (1.8%) and sinus bradycardia in one (0.9%). QTc prolongation was observed in 17.6% subjects. CV complications included acute cardiac injury in 25.9%, heart failure, cardiogenic shock and acute coronary syndrome in 3.7% each, “probable” myocarditis in 2.8% patients. Patients with acute cardiac injury had higher mortality than those without (16/28 [57.1%] vs 14/78 [17.5%]; P < 0.0001). Multivariate logistic regression analysis showed that acute cardiac injury (OR: 11.3), lymphopenia (OR: 4.91), use of inotropic agents (OR: 2.46) and neutrophil-lymphocyte ratio (OR:1.1) were independent predictors of mortality.
Conclusions
CV complications such as acute cardiac injury is common in COVID-19 patients and is associated with worse prognosis.
The ameliorative effect of Dalbergia sissoo, planted on sodic land at Sultanpur (26 10 0 -26 40 0 N, 81 45 0 -82 30 0 E), India, in a tropical environment, was studied at 3, 6 and 9 years of age. The soil properties of the sites improved significantly, showing marked reduction in pH, electrical conductivity (EC) and exchangeable sodium percentage (ESP) and an increase in organic carbon, nitrogen and availability of nutrients in the soil. The significant reduction in Na ion was found in all the age groups. Results showed an improvement in the soil moisture regime due to increased infiltration rate (cm hr À1 ), soil permeability (cm 2 ), water-holding capacity, field capacity and pore space whereas, the bulk density decreased significantly after successive years of planting. The effect on soil attributes was confined to surface soil in the young plantation and deeper in older plantation. Therefore, the study clearly indicated that the sodic soil could be desodified by growing D. sissoo plantations on these degraded sites.
The study was carried out in sodic lands of Sultanpur District, Uttar Pradesh, India. The barren soils and the soils supporting 3-, 6-and 9-year-old plantations of Prosopis juliflora (Swartz) D.C. and Dalbergia sissoo Roxb. Ex. D.C. plantations were examined to assess the rate and extent of changes undergone by physical and chemical properties of the soil. The study brought out that these species indicated the process of soil rehabilitation from the early stages of growth and the extent of rehabilitation increased with the age of the plantation. P. juliflora was found to be more efficient in reclaiming the soil in comparison to D. sissoo. The decline in soil pH and exchangeable sodium percentage (ESP) indicates the desodification and enrichment with organic C, N, P and K indicates improvement in nutrient status of the soil. After 9 years of planting the surface soil was completely desodified as indicated by pH (<8Á5), ESP (<15) and sodium adsorption ration (<15). A significant increase in organic C, exchangeable Ca 2þ and Mg 2þ and decrease in exchangeable Na þ reveals that the nutrient status is attaining suitable balance. The physical attributes of the soil also underwent improvement in terms of increase in porosity, water-holding capacity, field capacity and decline in bulk density. The flocculation of dispersed soil surface and improvement in soil structure was indicated by increased infiltration rate (cm h
À1) and soil permeability (cm 2 ).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.