Introduction: Fetal liver failure is a major cause of neonatal morbidity and mortality, presenting as acute liver failure and/or congenital cirrhosis. Gestational alloimmune liver disease associated with neonatal haemochromatosis is a rare cause of fetal liver failure. Case report: 24-year-old primigravida on Level II ultrasound scan showed intrauterine live fetus, with the fetal liver showing nodular architecture and coarse echotexture. Moderate fetal ascites were present. Scalp oedema was present with minimal bilateral pleural effusion. Suspicious fetal liver cirrhosis was raised, and the patient was counseled for a poor prognosis of pregnancy. Surgical termination of pregnancy was performed at 19 weeks through Cesarean section, and postmortem histopathological examination revealed haemochromatosis, hence gestational alloimmune liver disease was confirmed. Discussion: The presence of a nodular echotexture of the liver, with ascites, pleural effusion, and scalp oedema suggested chronic liver injury. Gestational alloimmune liver disease-neonatal haemochromatosis is often diagnosed late and patients are therefore referred late to specialized centers, delaying treatment. Conclusion: This case highlights the consequences of late diagnosis and treatment of gestational alloimmune liver disease-neonatal haemochromatosis and emphasizes the importance of a high grade of suspicion of this disease. Level II ultrasound scan should include scanning of the liver, as a part of the protocol. A high grade of suspicion is key for the diagnosis of gestational alloimmune liver disease-neonatal haemochromatosis, and early use of intravenous immunoglobulin should not be postponed to allow longer survival of the native liver.
Background. Cystic hygroma (CH), occurs in 1/6000 live births and in 90% of cases develops in age less than 2 years old. They are mainly located in cervicofacial region. Adult-onset CH is very rare. Objective. The aim of this study is to review literature to discuss the clinical presentation, diagnosis, and treatment of CH in adults through a case report of unilocular CH in the axillary region in an adult male from India. Methods. A first case report of unilocular CH in axillary region in an adult male from India is being investigated. Results. Here we report a case of unilocular CH in the axillary region in a 49-year-old male with a 14x16x8 cm cystic swelling in left axilla with a history of aspiration failure. Contrast-enhanced MRI (CEMRI) showed well-defined thin walled, unilocular cystic lesion which appeared hyperintense on T2 & STIR and hypointense on T1W1 and showed thin peripheral rim of enhancement on post contrast images. The patient underwent surgical excision and the diagnosis of a pathological CH was established. His postoperative recovery was uneventful and had no evidence of recurrence. Conclusion. Due to rarity of adult-onset unilocular CH in axilla, its evaluation for prompt diagnosis and definitive treatment to prevent recurrence and complications is urgent. Furthermore, this is the first reported case from India which has been successfully managed at a peripheral hospital in Northeast-India and our report of this case contributes to the evidences supporting the role of CH in a differential diagnosis for masses in the adult axilla, especially in acute phase with no predisposing factors.
Nоn-tubаl eсtорiс рregnаnсies, esрeсiаlly bilаterаl оvаriаn оnes, аre very rаre. In this саse reроrt, we рresent а саse оf sроntаneоus bilаterаl оvаriаn рregnаnсy in а 30-yeаr-оld multiраrоus lаdy whо рresented with а seven-dаy histоry оf lоwer аbdоminаl раin аssосiаted with fever. The urine рregnаnсy test wаs роsitive. The trаnsvаginаl ultrаsоund findings аlоng with the β-сhоriоniс gоnаdоtrорin level were indiсаtive оf а bilаterаl оvаriаn eсtорiс рregnаnсy, аnd the surgiсаl treаtment оf the раtient wаs deсided. Fоllоwing the раtient's соnsent, intrаорerаtively the рresenсe оf аn оvаriаn eсtорiс рregnаnсy wаs deteсted by the gyneсоlоgist аnd bilаterаl sаlрingо-оорhоreсtоmy wаs dоne. Оn histораthоlоgy, the findings reveаled trорhоblаstiс tissue аnd сhоriоniс villi аlоng with рrоduсts оf соnсeрtiоn in bоth оvаries, соnfirming the diаgnоsis оf bilаterаl sроntаneоus eсtорiс рregnаnсy. The раtient wаs disсhаrged frоm оur сliniс оn the fifth роst-орerаtive dаy, with instruсtiоns fоr regulаr fоllоw-uр оf the β-сhоriоniс gоnаdоtrорin level until it returns tо nоrmаl vаlues. Аn eаrly diаgnоsis leаds tо а signifiсаnt reduсtiоn in mоrbidity аnd mоrtаlity with suсh саses аnd helрs tо imрrоve their оverаll рrоgnоsis.
Introduction: Cavernous haemangioma is the most common benign non-infiltrative neoplasm of the orbit. Most cavernous haemangiomas are intraconal and lateral in location. Case report: We present a rare case of a cavernous haemangioma with an unusual location in the supraorbital region of the orbit, presenting with soft tissue swelling. Discussion: Cavernous haemangiomas are the most common benign non-infiltrative neoplasms of the orbit and have a slowly progressive mass effect. A slowly progressive proptosis is the typical presenting symptom. Extraocular muscle impairment and impaired visual function are seen with large lesions and with lesions located at the orbital apex. Most cavernous haemangiomas are typically intraconal and lateral in location. Extraconal and medial locations are uncommon. Ultrasound, computed tomography and magnetic resonance imaging are useful imaging techniques for the evaluation of such tumours. Treatment of the tumour is surgical excision. Complete excision is generally accomplished as the tumour is well-encapsulated with relatively few feeding vessels.
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