Oral pyogenic granuloma (PG) is traditionally treated by surgical excision which is associated with bleeding, pain and a high rate of recurrence. Our research aimed to clinically assess the effectiveness of diode laser versus sclerotherapy, as bloodless approach, in the treatment of oral PG. We randomly divided 20 patients with oral PG into two groups, with those in the test group being managed via diode laser application and those in the control group via injections of ethanolamine oleate as a sclerosing agent. All patients were evaluated intraoperatively for bleeding severity and postoperatively for pain. The quality of healing was also assessed using Landry healing index after the 1st, 2nd and 4th weeks. Additionally, the patients were recalled after 3, 6 and 9 months from the end of treatment for recurrence evaluation. Our results revealed that intraoperative bleeding did not differ significantly between both groups while postoperative pain decreased significantly in the sclerotherapy group compared to the laser group. For different intervals, the sclerotherapy group had a higher healing quality index than the laser group, although the difference was not statistically significant. However, recurrence occurred in the laser group, there were no cases of recurrence in the sclerotherapy group in all intervals. In conclusion, diode laser treatment of PG is a reliable, less invasive, and sensitive procedure that requires an experienced operator and specialised equipment. However, ethanolamine oleate sclerotherapy is an inexpensive, simple technique besides being less prone to recurrence problems, especially when treatment duration is not a concern.

INTRODUCTION: Pyogenic granuloma (PG) is a type of reactive hyperplasia that results in the enlargement of soft tissues. Oral PG is traditionally treated by surgical excision with a scalpel in addition to removal of the irritant or trauma source. Surgical removal of a pyogenic granuloma is associated with bleeding and pain. A high rate of recurrence is very common which might be due to incomplete removal. Sclerotherapy would be a good treatment choice for large-sized lesions. OBJECTIVE: To evaluate postoperative pain and recurrence using sclerotherapy versus conventional surgical excision in treating oral pyogenic granuloma. Materials and methods: 20 patients with pyogenic granuloma were enrolled in this randomized controlled clinical trial, divided equally into two groups. Group-I (test group) treated by Ethanolamine Oleate injection as a sclerosing agent. Group-II (control group) treated by surgical excision. Patients were evaluated in terms of pain at the 2nd and 7th day postoperatively and monthly for recurrence up to 6 months. RESULTS:The evaluated parameters demonstrated improvement by the end of the study in comparison to baseline, in terms of postoperative pain. None of the patients in test group reported recurrence at 6 months follow-up. On contrary 2 patients reported recurrence in the control group. However, there was no statistical significance between the two groups. CONCLUSION: Sclerotherapy is simple, inexpensive technique that showed no recurrence for treatment of oral PG.