Clinical involvement of the nervous system in visceral larva migrans due to

HAV was the main etiologic agent of ALF in the population studied.

In the streets of Vitória, in the State of Espírito Santo, Brazil, are large number of stray dogs, many of which are infected with Toxocara canis, suggesting a high risk for human infection. In order to investigate the prevalence of Toxocara infection in children in Espírito Santo we studied the prevalence of anti-Toxocara antibodies in 100 random inpatients over one year of age, at the Children's Hospital N.S. da Glória, the reference children's hospital for the State. All the sera were collected during the period between October 1996 and January 1997. The mean age was 6.6 +/- 4.1 yrs. (1 to 14 yrs., median 6 yrs.) and there were patients from all of the different wards of the hospital. Sixty-eight patients came from the metropolitan area of Vitória and the other 32 from 17 other municipalities. The anti-Toxocara antibodies were investigated by ELISA-IgG using a secretory-excretory antigen obtained from second stage larvae. All sera were adsorbed with Ascaris suum antigen before the test. Thirty-nine sera (39%) were positive, predominantly from boys, but the gender difference was not statistically significant (boys: 25/56 or 44.6%; girls: 14/44 or 31.8%; p = 0.311). The prevalence of positive sera was higher, but not statistically significant, in children from the urban periphery of metropolitan Vitória (formed by the cities of Vitória, Cariacica, Vila Velha, Serra and Viana) than in children from 17 other municipalities (44.1% and 28.1% respectively, p = 0.190). Although the samples studied do not represent all children living in the State of Espírito Santo, since the Children's Hospital N.S. da Glória admits only patients from the state health system, it is probable that these results indicate a high frequency of Toxocara infection in children living in Espírito Santo. Further studies of population samples are necessary to ascertain the prevalence of Toxocara infection in our country.

Cad. Saúde Pública, Rio de Janeiro, 32(9):e00118215, set, 2016Avaliação da cascata de cuidado na prevenção da transmissão vertical do HIV no Brasil Evaluation of the cascade of care in prevention of mother-to-child HIV transmission in Brazil Evaluación de la cascada de cuidado en la prevención de la transmisión vertical del VIH en Brasil

Objective: to analyze the spatial distribution of syphilis cases in pregnancy and congenital syphilis cases, from 2011 to 2018. Methods: this was an ecological study applying spatial analysis of syphilis cases in pregnancy and congenital syphilis reported on the Notifiable Diseases Information System; TerraView 4.2.0 software was used. Results: seventy-eight municipalities were analyzed, and evidence of a significant cluster was found for syphilis in pregnant women (Moran index=0.38; p=0.01) and for congenital syphilis (Moran index=0.31; p=0.01) in the greater Vitória region and north coast municipalities; along the north and metropolitan coastal regions some 30 municipalities were identified as having higher occurrence of the outcomes, as well as some 14 municipalities with a high proportion of congenital syphilis and a low proportion of syphilis in pregnancy. Conclusion: the study identified places where interventions and prenatal care professional training need to be channeled, with the aim of controlling syphilis in pregnancy and congenital syphilis.