A shelf-life study was carried out on fresh filled pasta in order to evaluate the presence of fungal contamination in the production process (environment, raw materials and finished products), with particular regard to the Penicillium genus. Analyses were conducted on three types of products, while air sampling was carried out in shaping processes and packaging areas. After isolation of molds, phenotypic identification of Penicillium genus and genotyping confirmation were carried out. As for the isolated strains, the species identified are those expected from this type of matrix: 40.7% P. viridicatum, 14.8% P. griseofulvum, 11.1% P. chrysogenum, 7.4% for P. citrinum, P. nalgiovense and P. crustosum and finally 3.7% for each of the three remaining species (P. roqueforti, P. formosanum, P. atramentosum). Results showed environmental contamination, particularly at the end of the work day. In fact, 59% of identified Penicillia originated from air samples, while only 10% from foods. Moreover, even if fungal contamination was observed at all considered times, level of contamination were generally low and never resulted in spoilage of the product as no macroscopically visible colonies were observed. It is therefore clear that pasteurization and modified atmosphere packaging are able to control the growth of potentially present fungal contamination

Hybrid lesions of the oral cavity are infrequent and share characteristics with a number of other pathologies. Both odontomas and dentigerous cysts are of odontogenic origin, but their simultaneous occurrence is rare and scarce. Clinical and radiographic examinations are not conclusive, making their identification difficult, while histopathological studies can reveal their defining characteristics. The aim of this report was to describe the radiographic and histomorphological findings of a hybrid lesion formed by a complex odontoma and a dentigerous cyst, affecting the mandible of a 22-yearold man, from Cartagena, Colombia, who had no relevant medical history, and no symptoms or discomfort in the affected area.

Se presenta el caso de un paciente con aspergilosis pulmonar crónica cavitada con ilustración imagenológica e histopatológica.

El Mioepitelioma es una neoplasia rara presente con mayor frecuencia en las glándulas salivales, representando el 1% de todos los tumores glandulares. Sin embargo, se han descrito también en localizaciones diferentes tales como piel, tracto gastrointestinal, pulmón, vía aérea superior, mama y tejido blando, existiendo escasos reportes en la literatura universal sobre casos a nivel del sistema nervioso central, pero ninguno específicamente a nivel hipofisiario. Se presenta el caso de una paciente femenina de 70 años de edad quien acude repetidamente al servicio de urgencias por cuadro clínico de cefalea intensa crónica de varios meses de evolución, la cual fue manejada con opioides sin resolución del cuadro, presentando de forma aguda perdida de la agudeza visual en ojo izquierdo y ptosis palpebral ipsilateral. Los hallazgos tomográficos revelaron discreto quiste retencional en seno esfenoidal derecho, mientras que la resonancia magnética nuclear evidencio tumoración en fosa media de base del cráneo, realizándose diagnostico presuntivo de adenoma hipofisiario. Se realizó una búsqueda sistemática utilizando descriptores tales como “Mioepitelioma”, “Encefalopatias”, “Hipofisis”, y “Colombia”, además de sinónimos tanto en inglés como en español, en bases de datos nacionales y Latinoamericanas, sin encontrar resultados relacionados, por lo que este caso constituye el primero en Colombia y sus alrededores.