In this study, the behavior of ginger flour (Zingiber officinale) was evaluated on the productive parameters during the first stage of laying in quail (Coturnix coturnix japonica), it was carried out in five phases distributed in weeks (phase one, 1 and 2, phase two, 3 and 4, phase three, 5 and 6, phase four 7 and 8 and phase five 9 and 10) of posture. The variables to be studied were: feed consumption (g) feed conversion, mortality, (%), percentage of laying (%), egg quality expressed in (egg weight (g) shell thickness (mm), resistance of shell (kgf), yolk coloration. A completely randomized design with four treatments and six repetitions was used, as well as an analysis of variance and Tukey's test at 5%. The treatments used were: T1, T2 and T3 T0 (control), were applied in doses of ginger flour of: 0%, 0.2%, 0.4% and 0.6% respectively. The statistical differences between T3 and the control group, determined that the flour favors the consumption of food, especially in the final phases of the study, (T1, T2 and T3) compared to the control group. Feed conversion shows significant differences with T2 in the intermediate production phases compared to the control. The percentage of laying does not present significant differences, in addition to the quality of the eggs improved notabl e mind. Regarding mortality, there were significant differences especially in T3 compared to the control since the birds showed resistance to diseases. In relation to profitability, the results of T3 were superior, with a CRB of 1.19. Concluding that the inclusion of ginger flour improves the productive parameters and the quality of the eggs 2021. Journal of the Selva Andina Animal Science ® . Bolivia. All rights reserved.

Con respecto a la Schizosaccharomyces pombe se han descrito tres cascadas de MAPKs: la de respuesta feromonas, con Spk1p como MAP kinasa; la de respuesta a estrés en la que Sty1p/Spc1p es la MAPK y la de mantenimiento de la integridad celular liderada por Pmk1p/Spm1p. La eliminación de cualquiera de las kinasas de la ruta de integridad provoca alteraciones morfológicas y células multitabicadas en condiciones de estrés; lo que sugiere una función en homeostasis iónica y en la biosíntesis de la pared celular por lo que se propuso estudiar el papel de la ruta de señalización de MAPK Pmk1p en el mantenimiento de la integridad celular en S.pombe. El organismo mayoritariamente utilizado fue la levadura de fisión S. pombe y para realizar los trabajos de clonación molecular se utilizaron también diferentes estirpes de Escherichia coli. Se emplearon diversas técnicas de clonación molecular, métodos genéticos, Western Blot y determinación de la actividad de Pmk1p bajo condiciones de estrés. Las conclusiones más importantes fueron: que los “sensores” “Mtl2p y Wsc1p” señalizan hacia Rho1p pero no son componentes “auténticos” de la cascada, y sus mutantes no presentan el fenotipo vic (viable en presencia de inmunosupresor y de iones cloruro), característico de los mutantes en los componentes de la cascada. Mtl2p y Wsc1p no desempeñan un papel importante en la señalización en respuesta a estrés osmótico y daño en la pared celular a través de la ruta de integridad celular de Pmk1p.

In this study, the behavior of ginger flour (Zingiber officinale) was evaluated on the productive parameters during the first stage of laying in quail (Coturnix coturnix japonica), it was carried out in five phases distributed in weeks (phase one, 1 and 2, phase two, 3 and 4, phase three, 5 and 6, phase four 7 and 8 and phase five 9 and 10) of posture. The variables to be studied were: feed consumption (g) feed conversion, mortality, (%), percentage of laying (%), egg quality expressed in (egg weight (g) shell thickness (mm), resistance of shell (kgf), yolk coloration. A completely randomized design with four treatments and six repetitions was used, as well as an analysis of variance and Tukey's test at 5%. The treatments used were: T1, T2 and T3 T0 (control), were applied in doses of ginger flour of: 0%, 0.2%, 0.4% and 0.6% respectively. The statistical differences between T3 and the control group, determined that the flour favors the consumption of food, especially in the final phases of the study, (T1, T2 and T3) compared to the control group. Feed conversion shows significant differences with T2 in the intermediate production phases compared to the control. The percentage of laying does not present significant differences, in addition to the quality of the eggs improved notabl e mind. Regarding mortality, there were significant differences especially in T3 compared to the control since the birds showed resistance to diseases. In relation to profitability, the results of T3 were superior, with a CRB of 1.19. Concluding that the inclusion of ginger flour improves the productive parameters and the quality of the eggs 2021. Journal of the Selva Andina Animal Science ® . Bolivia. All rights reserved.