RATIONALE: Peach tree (PT) pollen is entomophilous and therefore elicits allergy only in occupational exposure. METHODS: We report two cases of 12 y.o. girl and 15 y.o. boy living in an area of PT cultivars that in the past four-five years have developed rhinitis and, in the first case, also asthma. Symptoms appeared mainly on visits or stays in the family farms in the period of Peach tree (PT) flowering from late February to early June. RESULTS: Skin prick test (SPT) were positive to olive, grass, S kali and PT pollen in Case 1 and to S kali and PT pollen in Case 2. In both cases, SPT were negative to peach fruit and Pru p 3. SDS-PAGE immunoblotting showed one band recognized by rabbit polyclonal antisera to Ole e 6 and identified like Ole e 6-like allergen. We did SPT with Pru p 9, an already identified and registered allergen from PT pollen, plus Ole e 6-like having a positive response to both in Case 1 and only to Ole e 6 like in Case 2. Nasal challenges with PT pollen and Ole e 6 like were positive in both cases whereas with Pru p 9 and Olive tree pollen only in Case 1. CONCLUSIONS: These results show that PT pollen can induce symptoms in children living in an area of PT cultivars and children directly or indirectly exposed must be evaluated. We prove for the first time allergy to Ole e 6-like from PT pollen in children.

Brassiea seed oils, like rape, mustard, ravison, etc.,

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