Authors' contributions: Sangamitra Rajasekaran and Mayur Parkhi contributed to the analysis of the pathologic findings and to manuscript writing. Aravind Sekar and Ritambhra Nada verified the histopathological aspects and edited the manuscript. Ravi Kanojia collected and critically analysed clinical data.
Introduction
Adenoid cystic carcinoma (ACC) is a ubiquitous tumour which can occur in several sites of the human body. Commonly, it affects the salivary glands but also can rarely occur in various extra‐salivary locations.
Aim
To study the clinical and cytological features of extra‐salivary ACC on fine needle aspiration cytology.
Methods
In this paper, we included 27 patients with extra‐salivary ACC on fine needle aspiration cytology over a period of 5.5 years. The complete cytomorphological spectrum of extra‐salivary ACC was studied.
Results
The mean age of the patients was 50.2 years, with age ranging between 14 and 80 years. Male to female ratio was 1:1.7 with 17 females and 10 males. The most frequent primary site was the orbit, and the most frequent sites of metastasis were liver and lung.
Conclusion
Cytopathologists should be alert about the full range of location as well as the cytological spectrum of extra‐salivary ACC for greater precision in diagnosis and prompt treatment.
A 60-year-old female presented with bleeding per vaginum, loss of weight, and loss of appetite for the previous 2 months. She had undergone a hysterectomy with bilateral salpingo-oophorectomy 15 years prior for abnormal uterine bleeding; however, no radiological or histopathological details were available. On examination, a pelvic mass equivalent in size to a uterus at 12-14 weeks' gestation was noted. On examination per speculum, the vault was replaced by a friable, irregular mass that bled when touched. Computerised tomography (CT) of the abdomen revealed an irregularly marginated,
Primitive myxoid mesenchymal tumor of infancy (PMMTI) is a recently described entity, previously included under the umbrella of undifferentiated sarcomas. These tumors are notorious for recurrence, chemoresistance and may even metastasize. We describe here, for the first time, the cytomorphology of PMMTI. Further, we discuss the morphological differentials and relevant immunocytochemical markers to reach a correct diagnosis. Knowledge about the distinctive cytomorphological features with characteristic immunocytochemistry is the key to the challenging diagnosis of PMMTI. Establishing the diagnosis on cytology is not difficult in cases of recurrence when such a history is forthcoming. These tumors are a rarity, and awareness of cytomorphology and employment of ancillary techniques is diagnostic, guiding the appropriate therapeutic management.
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