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To find out the levels of IL-8 in patients of chronic pelvic pain & infertility & assess its role in predicting endometriosis. It was a prospective study conducted over 50 patients of chronic pelvic pain & infertility undergoing diagnostic laparoscopy. During this procedure peritoneal fluid &blood samples were collected & prepared for ELISA, IL-8 estimation. Serum IL-8 levels of >22.16 pg/ml& peritoneal fluid level of >7.98 pg/ml were found to be 100% sensitive & specific .Thus they can be taken as cut-off value for predicting endometriosis. IL-8 was significantly elevated in the serum & peritoneal fluid in the patients of endometriosis diagnosed by diagnostic laparoscopy. Our study indicates that serum & peritoneal fluid IL-8 levels can discriminate patients with& without endometriosis and could serve as one of the non-invasive ideal markers to cut short the delay in the diagnosis & management of infertility and also lays down a foundation for further research in correlating IL-8 levels with disease severity

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BACKGROUND: In India; the high rate of infant and maternal mortality, may be attributable to rising trend of GDM across Pregnant women. Therefore the study of management of GDM by existing health facilities and Community camps in government and private sector becomes crucial for managing such cases. The present study by prospective evaluation method saught to find out the management of GDM for implementing GDM screening in Kanpur. METHODS: A prospective evaluation based study was done from October, 2012 to September, 2014 at 198 healthcare facilities and 454 screening camps in Kanpur Nagar on 57,018 pregnant women, who were screened between 24th-28th weeks of pregnancy as per DIPSI & FOGSI guidelines. RESULTS: The total pregnant women who were Diagnosed as GDM were 7641 (13.4%) and this prevalence of GDM was more in urban area(16%) as compared to rural area(9.8%). The health facilities in combined more were more efficient in diagnosing GDM(86%) as compared to Commmunity camps(14%)(p<0.0001), but facilities were least interested in follow-up of Blood glucose Monitoring and further counselling (10%). In public health facilities howver-21% Pregnant women attending OPD were under gone OGTT as compared to 7% in Private health facilities and they tested OGTT more than the private health facilities. CONCLUSION: Public health system role is management of GDM is more significant as compared to Community level camps. There are potential benefits of actively involving Public health facilities in GDM Management among pregnant women, which needs to be taken care by Government on priority basis.

Background: Cesarean section is the commonest procedure in Obstetric practice and postoperative pain can be a major factor for wound healing as well as mother and baby bonding. Spinal anesthesia is considered to be safest and easiest modality for cesarean section cases. Bupivacaine is the commonest drug given in spinal anesthesia, but many additive drugs have been introduced to cover post-operative analgesia. Clonidine is an alpha 2 agonist which can be used as an adjunct to heavy bupivacaine to extend analgesic effects.Methods: A randomized double-blind study was performed in 100 women undergoing elective cesarean section under spinal anaesthesia. After proper informed written consent patient undergoing cesarean section were divided by computerized method into group A (Given 10.0 mg 0.5% hyperbaric Bupivacaine) and Group B (Given 9.0 mg 0.5% hyperbaric bupivacaine and 30 μg clonidine).Results: Intraoperative hypotension is the most worrisome factor but it is transient and can be managed by ephedrine effectively. Intraoperative nausea and vomiting are slightly higher with clonidine as occurrence of hypotension is more. VAS scoring in post-operative period was better and need of first analgesic dose was much delayed in women been given clonidine with bupivacaine.Conclusions: Clonidine can be considered as adjunct in spinal anesthesia to extend post-op analgesic cover.