While neural networks have advanced the frontiers in many machine learning applications, they often come at a high computational cost. Reducing the power and latency of neural network inference is vital to integrating modern networks into edge devices with strict power and compute requirements. Neural network quantization is one of the most effective ways of achieving these savings, but the additional noise it induces can lead to accuracy degradation. In this white paper, we present an overview of neural network quantization using AI Model Efficiency Toolkit (AIMET). AIMET is a library of state-of-the-art quantization and compression algorithms designed to ease the effort required for model optimization and thus drive the broader AI ecosystem towards lowlatency and energy-efficient inference. AIMET provides users with the ability to simulate as well as optimize PyTorch and TensorFlow models. Specifically for quantization, AIMET includes various post-training quantization (PTQ, cf. chapter 4) and quantization-aware training (QAT, cf. chapter 5) techniques that guarantee near floating-point accuracy for 8-bit fixed-point inference. We provide a practical guide to quantization via AIMET by covering PTQ and QAT workflows, code examples and practical tips that enable users to efficiently and effectively quantize models using AIMET and reap the benefits of low-bit integer inference.