Anesthetic drugs must be administered at an appropriate rate to prevent adverse reactions during ambulatory surgery and after discharge from the hospital. Target Controlled Infusion (TCI), choose the target concentration and infusion pump deliver the dose to patient. TCI helps to avoid underdose or overdose. The anesthetic drug Propofol (Diprivan) slows the motion of patient's brain and nervous system. Target controlled infusion (TCI) of propofol permit anesthetists to target constant blood concentrations and react punctually to signs of inappropriate anesthetic depth. Target Controlled Infusion (TCI) induces and preserves a drug concentration by using an internal three compartmental pharmacokinetic model. In this paper, the drug concentration which is deliver to patient is controlled by the controller, implemented on embedded system. The results shows that better accuracy is achieve with TCI as compared to manual infusion.

The positive output elementary Luo (POEL) converter is a fourth-order DC–DC converter having highly non-linear dynamic characteristics. In this paper, a new dynamic output voltage feedback controller is proposed to achieve output voltage regulation of the POEL converter. In contrast to the state-of-the-art current-mode controllers for the high-order boost converters, the proposed control strategy uses only the output voltage state variable for feedback purposes. This eliminates the need for the inductor current sensor to reduce the cost and complexity of implementation. The controller design is accompanied by a strong theoretical foundation and detailed stability analyses to obtain some insight into the controlled system. The performance of the proposed controller is then compared with a multi-loop hysteresis-based sliding-mode controller (SMC) to achieve the output voltage-regulation of the same POEL converter. The schemes are compared concerning ease of implementation, in particular, the number of state variables and current sensors required for implementation and the closed-loop dynamic performance. Experimental results illustrating the features of both controllers in the presence of input reference and load changes are presented.

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