Closed injuries to the peroneal nerve recover spontaneously in about a third of patients, but surgery may be needed in the remaining 2/3. The recovery after surgery is not always satisfactory and the patients may need an orthosis or a walking aid to cope with regular daily activities. This study aimed to evaluate the useful functional recovery and quality of life (QoL) in surgically treated patients with peroneal nerve (PN) injuries. The study involved 51 patients who have undergone surgical treatment due to PN injury in our department, within a 15-year period (2006–2020). Thirty patients (59%) were treated with neurolysis, 12 (23%) with nerve repair techniques, and 9 (18%) with tendon transfer (TT). Neurolysis is employed in the least extensive nerve injuries when nerve continuity is preserved and yields a motor recovery ratio of almost 80%. Nerve repairs were followed by 58.33% of patients achieving M3+ recovery, while 41.66% recovered to the useful functional state (M4 or M5) With the use of TTs, all patients recovered to the M3+, while 66.7% recovered to M4. All our results correspond to the results of previous studies. No statistically significant differences were found regarding the QoL of the groups. There is an apparent advantage of neurolysis, over nerve repair, over TT procedure, both in terms of useful functional recovery, and foot-drop-related QoL. However, when involving all aspects of QoL, these advantages diminish. The individual approach leads to optimal results in all groups of patients.

ObjectiveAlthough the studies have shown the beneficial effects of diet, nutrition, and supplementation as an independent treatment modality, their roles are underestimated in the treatment of peripheral nerve injuries. This is in great part due to the development of efficient nerve repair techniques, combined with physical treatment and stimulation. To achieve the best possible functional recovery diet, nutrition, and supplementation should be implemented within a multidisciplinary approach. The aim of the study is to provide insight into the potentially beneficial effects of diet, nutrients, and supplementation, in the limitation of nerve damage and augmentation of the functional recovery after surgery in a review of human and animal studies.MethodsThe data relating to the diet, nutrients, and supplementation effects on peripheral nerve injuries and their treatment was extracted from the previously published literature.ResultsGeneral balanced diet as well as obesity influence the initial nerve features prior to the injury. In the period following the injury, neuroprotective agents demonstrated beneficial effects prior to surgery, and immediately after the injury, while those potentiating nerve regeneration may be used after the surgical repair to complement the physical treatment and stimulation for improved functional recovery.ConclusionsStandardized diet, nutrition, and supplementation recommendations and protocols may be of great importance for better nerve regeneration and functional recovery as a part of the multidisciplinary approach to achieve the best possible results in surgically treated patients with peripheral nerve injuries in the future.

Introduction. Chronic pancreatitis (CP) causes inflammatory changes in the tissue of the pancreas, resulting in irreversible tissue damage. Pain, endocrine, and exocrine pancreatic insufficiency develop, thereby reducing the quality of life of patients. The study aims to explore the role of surgical treatment in improving the quality of life of patients with CP. Methods. Quality of life assessment of 50 patients diagnosed with CP was performed using a certified Euro Quality of life-5 dimension-5 level questionnaire translated into Serbian (EuroQol-5D-5L). Patients completed the questionnaire. Patients were divided into two groups (conservative - CT vs. surgical - ST), and all comparations was made between groups. Results. Patients in stage B chronic pancreatitis were divided into two groups of 25 patients. The first group of patients with CP was treated with conservative, and the second group with surgical approach. Mane age in surgically treated (ST) group was 48.56 ? 11.91, and in conservatively treated (CT) group was 51.08 ? 11.61 (p=0.452). Male/female ratio in ST group was 18/7, and in CT group was 22/3 (p=0.289). Pain in ST group was present in 23 patients, and in CT group was present in 18 patients (p=0.141). Loss of appetite in ST group was present in 7 patients, and in CT group was present in 10 patients (p=0.256). Weight loss in both groups was equal (p=1.000). Based on EuroQol-5D-5L it was found significant differences (p<0.001) between group in Mobility and Pain / Discomfort; in Anxiety / Depression (p=0.003); in Self-care (p=0.004); in Usual activities (p=0.008). Conclusion. CP significantly reduce the quality of life (QoL) of patients treated conservatively or by surgical approach. This study showed that surgical treatment is more beneficial in QoL in patients with CP then conservative approach

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