Diagnosing fetal syndromes is a major challenge both in the prenatal and postnatal period2. The syndrome is like a big puzzle whose parts need to be carefully assembled to get a whole picture. 2 Good multidisciplinary approach, proper communication and collaboration with parents and all physician's involved are required in the diagnostic process. All available resources and tools are needed to increase diagnostic precision in the prenatal diagnosis of fetal syndromes. 4 The introduction of highly specialized software systems for three-dimensional and four dimensional ultrasound (3D/ 4D US) enable detailed assessment of the fetal anatomy and the evaluation of the dynamics of structural and functional development of the fetus in real-time. 2,4 Owing to this, clinical practice has also gained new functional tests such as the Kurjak's antenatal neurodevelopmental test (KANET); named in honor of its author; used for the evaluation of fetal brain function. 2-4,24-31 Antenatal detection and diagnosis of fetal anomalies and syndromes is shifted from the 2nd to the 1st trimester of preg

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