Angular cheilitis is inflammation of the skin, occurring at the labial commissure -the angle of the mouth. It is an eroded and erythematous non-vesicular lesion that can occur at one or both corners of the mouth. The point of interface for squamous epithelium of the face and oral mucosa is at the angle of the mouth . It is also a mechanically dynamic hinge for the oral aperture that endures more motion and tensile forces than the rest of the lips. Thus, the commissures are especially susceptible to certain stresses. Other names for angular cheilitis include angular cheilosis, angular stomatitis, commissural stomatitis, rhagades, or perleche. The increased prevalence is associated with human immunodeficiency virus, usage of immunosuppressants and corticosteroids, increased usage of oral prosthesis in the elderly, xerostomia, expanded usage of oral antibiotics, obesity and diabetes to name a few. In young children, angular cheilitis is associated with habitual lip licking, thumb sucking, or biting of the corners of the mouth, whereas in older patients it occurs from sagging at the commissures of the mouth. The aim of this study was to assess the prevalence of angular cheilitis and assessment of factors associated with it. A retrospective study was conducted in the Saveetha Dental College, Chennai, India. Ethical clearance was obtained from SRB committee, Saveetha Dental College, Chennai, India. The clinical portion of this retrospective study was conducted over a 9 month period,i.e, between June, 2019 to March,2020. Some patients reported with pain while for others it was observed during routine examination. Data was collected from a total of 86000 patients who visited Saveetha dental college between Jun,2019 to March,2020. Out of this, the data of 57 patients who visited the institute and were diagnosed with angular cheilitis were retrieved. The data obtained was tabulated in SPSS for windows, version 20. Descriptive statistics were analysed. Chi square test was done to analyse association of habits of the patient with age, gender,dental status and systemic diseases of patients with angular cheilitis. The results of the study indicated angular cheilitis was more predominant in males and it was more predominant between 40-49 years of age. Angular cheilitis was more predominant in completely edentulous patients and diabetes was the most common systemic disease among the patients. There was statistically significant association between gender (P=0.002) and habits of the patient. However, there was no statistically significant association between age(P=0.278), dental status (P=0.137) and systemic diseases (P=0.817) with habits of the patient.