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Background: Laparoscopic surgery in cases of periampullary region malignancies has been emerging as a preferable alternative to open pancreatoduodenectomy due to their benefits such as early mobilization and shorter duration of hospital stay. We conducted this study to determine whether laparoscopic approach is comparable to open pancreatoduodenectomy in terms of hospital stay, blood loss, complications, pathological radicality with oncological safety and overall postoperative short-term outcomes.Methods: This was a single-center, non-stratified, balanced allocation, open-label, parallel-group randomized control study in which patients who had undergone  Whipple’s procedure were included. Patients were randomized after confirmation of non-metastatic status into either the laparoscopy (N=15) or open surgery group (N=15). The primary outcome variable was duration of postoperative hospital stays. Secondary outcomes were duration of surgery, blood loss, complication rates (using definitions of the international study group of pancreatic surgery) and pathological radicality of resection.Results: Pain in abdomen was the predominant complaint which was seen in 12 (80%) and 10 (66%) patients each. The other common symptoms were weight loss, vomiting and jaundice. Surgical site infection, mean blood loss and mean operative duration was significantly lower in laparoscopic group (P<0.05). Mean tumor size was more in open group. Mortality was comparable in both the groups.Conclusions: Laparoscopic pancreatoduodenectomy offers significant benefit in terms of hospital stay, surgical site infection, mean blood loss, mean operative duration and mean interval of duration receiving chemo/radiotherapy as compared to open surgery in cases of periampullary region malignancy.

Introduction: Obstructive jaundice is caused by defective transport of conjugated bilirubin from hepatic cells to the second part of duodenum. It is not a diagnosis in itself and

Background: Pancreatic pseudocysts can be defined as localized fluid collections that have a nonepithelialized wall consisting of fibrous and granulation tissue. These pseudocysts usually appear several weeks after the onset of pancreatitis. Advancement in the management of pseudocyst with laparoscopic drainage provides a good alternative or supplement to the surgical treatment of pancreatic pseudocyst. The purpose of this study is to evaluate the feasibility, effectiveness and outcome of Laparoscopic drainage.Methods: It was a prospective interventional hospital based study carried out among 32 indoor cases of pancreatic pseudocysts operated using laparoscopic procedures admitted under department of general surgery in a tertiary healthcare teaching institute during study period. Cases of pancreatic pseudocysts were evaluated with detailed history, clinical signs and symptoms, the duration and investigations. Details of laparoscopic, its indications, peculiarities, complications rates, recurrence rate and outcome was analyzed.Results: Single and multiple pancreatic pseudocysts were found in 26 (81.25%) and 6 (18.75%) patients and the most common site was found to be body of pancreas (59.37%). Obstructive jaundice (18.50%) and gastric outlet obstruction (15.63%) were the most common complications seen. The common procedures undertaken in the studied cases were laparoscopic cystogastrostomy (65.62%) followed by laparoscopic cystojejunostomy (12.50%) and laparoscopic external drainage (12.50%). Common complications in studied cases were found to be pain (15.65%), fever (12.5%) and external fistula (6.25%).Conclusions: Laparoscopic technique for treatment of pancreatic pseudocysts is safe, efficacious, feasible and is associated with fast recovery. These techniques should be preferred over open surgical drainage.