Purpose: Pheochromocytoma and paraganglioma (PGL), together called PPGL, are rare tumors with a limited number of studies on the diagnostic performance of 68 Ga-DOTA (0)-Tyr (3)-octreotate positron emission tomography-computed tomography ( 68 Ga-DOTATATE PET/CT) from the Asian-Indian subcontinent. Materials and Methods: In this retrospective study, PPGL suspects ( n = 87) who had undergone at least contrast-enhanced computed tomography (CECT) and 68 Ga-DOTATATE PET/CT, were included. Lesion-wise, patient-wise, and region-wise sensitivities of 68 Ga-DOTATATE PET/CT, 18 F fluorodeoxyglucose positron emission tomography CT ( 18 F-FDG PET/CT, n = 53), 131 I-metaiodobenzylguanidine ( 131 I-MIBG, n = 37), and CECT were compared, and diagnostic performance of 68 Ga-DOTATATE PET/CT in the detection of PPGL was calculated. Results: 68 Ga-DOTATATE PET/CT had significantly higher lesion-wise sensitivity than 131 I-MIBG for both primary (94% vs 75%, P = 0.004) and metastatic disease (85% vs 59%, P = 0.001) and higher sensitivity than CECT for metastatic lesions (83% vs 43%, P = 0.0001). The lesion-wise sensitivity of 68 Ga-DOTATATE PET/CT was similar to 18 F-FDG PET/CT for both primary tumors (94% vs 85%, P = 0.08) and metastatic lesions (82% vs 84%, P = 0.76) in the whole cohort but tended to be inferior in the head to head comparison. Conclusion: 68 Ga-DOTATATE PET/CT had higher sensitivity for detection of PPGL than 131 I-MIBG (primary and metastatic) and CECT (metastatic) but similar to 18 F-FDG PET/CT (primary and metastatic).