Level II, prospective randomized comparative series.

Melanotic neuroectodermal tumor of infancy is a rare, distinctive neoplasm of early infancy with rapid expansile growth and a high rate of recurrence. Most commonly, the lesion affects the maxilla of infants during the first year of life. One such case was diagnosed in the Department of Oral Pathology and Microbiology in Subharti Dental College, Meerut.

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Purpose: The aim of this study was to evaluate the efficacy of plateletrich fibrin (PRF) in the management of alveolar osteitis and further compare the results with those of zinc-oxide Eugenol (ZOE). Materials and methods: A total of 40 patients with alveolar osteitis following extraction of mandibular molars were randomly divided into two groups on the basis of treatment, in which Group A patient's received PRF and Group B received ZOE as an obtundant dressing. Pain (VAS), degree of inflammation and number of exposed socket walls were noted and evaluated at 1st, 3rd, 5th and 7th post-operative day. Results: Group A showed better and faster socket healing than Group B. However, symptomatic pain relief was faster in Group B than in Group A. Conclusion: PRF might be a treatment of choice in the management of alveolar osteitis. Clinical relevanceScientific rationale for study PRF is a healing bio-material. The rationale for using PRF in our study was based on previous studies, which showed the potential of PRF in the process of bone and soft tissue healing. Principal findingsIn our study, we found that PRF was better and faster than standard ZOE dressing in terms of reduction of inflammation and socket healing and equally effective as ZOE dressing in terms of pain control, in case of alveolar osteitis. Practical implicationsPRF has a simple and inexpensive processing, without biochemical blood handling. There is virtually no risk of allergic reactions. So, PRF might be a good alternative to ZOE in the management of alveolar osteitis.

The patients have completed a follow-up of 24 to 64 months (median, 38.5 months). Of the 44 patients, 12 had bilateral involvement. Trauma in childhood was, expectedly, the most frequent etiologic factor. Gap arthroplasty was the most frequently employed technique, followed by the use of autologous tissue interposition. The temporalis muscle-fascia and the temporalis fascia alone, as well as the auricular cartilage, were employed most frequently. Complete alloplastic condylar replacement was performed in one patient, who, unfortunately, returned with pain, clicking, and deviation of the jaw, necessitating removal within 1 month. Total joint replacement was abandoned after this case. We outline our protocol for the management of this disabling condition.