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Objective: The main objective of this research work is to synthesize a novel stannane of pyridoxal 5-phosphateand to study its antibacterial property. Methods:Conventional method was used to synthesize the stannane of pyridoxal 5-phosphateand its characterization was carried using UV-visible and 1Results: It was observed that the stannane of pyridoxal 5-phosphateinhibited bacterial growth of Staphylococcus aureus (gram positive) and Escherichia coli 1610 (gram negative) in vitro antibacterial study. The complex has shown good docking results on almost all the receptors, with interaction supporting the fitting of the drug to the target molecules. The novel complex has shown good antibacterial activity (theoretically) in insilico studies. It was found to having a good potency to efficiently inhibit the microbes Burkholderia pseudomallei, Human cytomegalovirus, Yersinia enterocolitica and Escherichia coli, based on the interaction profile. The synthesized stannane was found to be effective in halting the undesirable effects of selected PDB files.H NMR. The antibacterial study was carried against, Staphylococcus aureus (gram positive) and Escherichia coli 1610(gram negative) using well diffusion method. In silico antimicrobial was carried out using computational software iGemDock v2.1 tool.(Graphical Drug Design system for Docking, Screening, and Post-analysis), computational docking was carried out using different PDB (Protein Data Bank) files (2I42, 3EOO, 3D2U and 3D2Y). The structure was optimized prior docking using Gaussian software, and the method followed was Energy (Ground state) Hartree-Fork. Conclusion:On the basis of the above findings in the present research work, the novel complex was found to be a good antimicrobial agent and our future studies will aim design of novel selective and potent inhibitors. Further in vitro studies of this compound against these bacteria will lead to a new pathway to a novel antibacterial drug discovery.

Cellulose acetate (CA) membranes prepared by wet phase inversion technique were subjected to deposition of multilayer of Cu 2 [Fe (CN) 6 ] of different molar concentration (0.1m, 0.01m, 0.001m) by using the solution of potassium ferro cyanide and copper sulphate on the surface of CA membrane by alternate changing the two solutions in a special glass cell. This surface modification converted the CA membrane into nanofilters of more gelatinous texture and exact semipermeability. Electrochemical characterization of nanofilters has been attempted by calculating the values of transport number, fixed charge density and permselectivity using the data of mixed membrane potential across normal and surface modified membranes with electrolytic solutions of NaCl and KCl. The results showed that the presence of additional electrolyte, even of the same concentration on the both sides of membrane, significantly influences electrochemical character of nanofilter. Scanning electron microscopy (SEM) of the prepared nanofilter showed the resembling morphology and nanoporous surface texture of nanofilters with the deposition of multi electrolytic layers. The study successfully demonstrated the effect of simultaneous multi-ion transport across the nanofilters to pave mile stone of its applicability in selective recognition and filtration aspects.

We study control of chaos by periodic modulation without feedback in discrete maps. We show that period-p forcing shifts and splits the naturally occurring period-p windows (and their multiples) and leads to the stabilization of chaos, and that for multiplicative sinusoidal perturbations of the logistic map stabilization can be done at a desired value of the control parameter and at a desired periodicity, simply by varying the amplitude of forcing, provided the modulated system remains bounded.