Background: Since covid has emerged as the most dreadful global health crisis and data on diagnostic profile and morbidity mortality indicators in it is still limited, we propose to study the correlation of morbidity and mortality with values of Inflammatory markers in these patients. To STUDY variations in INFLAMMATORY MARKERS IN Aim: COVID19 PATIENTS and correlating it with severity of disease. using CLIA technique, four Materials and Methods: inflammatory markers ( TROPONIN -I , ferritin, procalcitonin, IL -6) were studied among 400 patients. This was correlated with severity of the disease outcome among the patients. Among the inflammatory markers we studied Results: IL-6 ,Ferritin,Troponin -I ,Procalcitonin. Raised values of IL-6 and raised ferritin levels were associated with severity. Troponin I (91%) ,Ferritin( 70.8%) ,Calcitonin ( 78.5%) were increased but showed no association with mortality. However only IL-6 seems to be associated with increased mortality among Covid patients. On the basi Conclusion: s of findings in this study Inflammatory markers particularly IL -6 and ferritin can be concluded as important predictors of disease severity and outcome.These parameters can be used to identify high-risk patients at resource-limited settings
Background: Since covid has emerged as the most dreadful global health crisis and data on diagnostic profile and morbidity mortality indicators in it is still limited, we propose to study the correlation of morbidity and mortality with values of Inflammatory markers in these patients. To STUDY variations in COAGULATION AND HEMATOLOGI Aim: CAL PROFLE IN COVID-19 PATIENTS and correlating it with severity of disease. using STA Satellite Materials and Methods: automated coagulation analyzer we study PT, INR, APTT. With the help of Snibe maglumi 800 we studied D-dimer. For hematological analysis we use Hemax 330 hematological analyzer for HB, TLC, Neutrophil and Lymphocytes count, Neutrophil lymphocyte ratio, Platelets count. In hematological profile leucocytosis was associated w Results: ith severity and mortality. In coagulation profile D-dimer was associated with severity and mortality. Overall only leukocytosis and raised D-dimer values were associated with death. On the basis of findings in this Conclusion: study coagulation profile and hematological profile Leucocytosis and D-dimer concluded as important predictors of disease severity and outcome.These parameters can be used to identify high-risk patients at resource-limited settings
Introduction: In recent years, complete blood count, red blood cell histogram and peripheral blood smear have become important diagnostic tools for diagnosing various blood diseases. Anemia is a major public health problem worldwide, with high prevalence in developing countries like India1. Red blood cell count and histograms are essential for the diagnosis and management of anemia2. The most important diagnostic tool for testing in most commercial laboratories is the periodic analysis of blood lms. AIM: the aim of this study was to compare the role of automated cell count histograms and peripheral blood smear results in the diagnosis of anemia.. Material and method:A prospective comparative study of RBC histogram and peripheral blood smear in diagnosis of anemia was done on 900 patients of HB<14gm%, over two month time span(September 2022-October 2022) in the central laboratory lab, Department of pathology, Gajra Raja Medical College, Gwalior, Madhya Pradesh. All cases of anemia who received blood transfusions were excluded from this study. Result:It was observed in our study that on peripheral blood smears, the most common type of anemia was microcytic hypochromic anemia, followed by normochromic normocytic anemias. When we compared with the histogram generated by the automated cell counter, the most common type of anemia was hypochromic microcytic anemia, followed by normochromic normocytic anemia. In our study, the female population was more numerous than the males. The average age is (23 years old). Conclusion:CBC histograms and peripheral blood smears generated by automated cell counters play an important role in the diagnosis and management of red blood cell disorders. Our study observed that the histogram pattern and its conrmation by the peripheral blood smear along with the clinical medical history allow an accurate and conrmed diagnosis of various blood disorders. Accuracy and precision have been greatly improved resulting in reducing the subjective error3 .
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