Patients with an ectopic pregnancy were studied for documentation of the site of ovulation in order to determine the frequency with which controlateral ovulation and ovum transport occurs. Analysis of data on 135 patients in whom the site of ovulation was documented at the time of surgery and on 24 patients who were studied ultrasonically before surgery indicates that contralateral ovulation and ovum transport occurs in at least a third of ovulatory events.

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Introduction: Preterm prelabor rupture of the membranes (PPROM) refers to spontaneous rupture of membranes in the absence of labor pains, before 37 completed weeks of gestation. Chorioamnionitis (CAM) affects many pregnancies complicated by PPROM. Finding a serum factor that could accurately predict the presence of CAM could potentially lead to more efficient management of PPROM and improved neonatal outcomes. It has been claimed that estimation of C-reactive proteins (CRP) is helpful in the diagnosis of chorioamnionitis, and this study aims to appraise such claimsObjective: To determine the diagnostic accuracy of C-reactive protein in the detection of chorioamnionitis in women with PPROM and to test sensitivity/specificity/positive predictive valve/negative predictive value of CRP in diagnosing chorioamnionitis against histopathological examination of placenta.Method: A study conducted on total 440 antenatal women, 220 cases of PROM and 220 cases with same gestation but without PPROM used as a control. A detailed obstetrical and menstrual history was taken and systemic and local examination was done. Subjects were managed expectantly with use of tocolytics, antibiotics and steroids. Frequent vital signs monitoring and hematological investigation were done. CRP levels were determined. After delivery placenta was sent for histopathological examination for the presence of chorioamnionitis.Results: CRP appears to be the most sensitive acute phase protein; rising of less than 24 hours makes it suitable to serve as a marker for diagnosing an infection. On comparing C-reactive protein levels with other laboratory tests and indicators of infection (e.g. total leucocyte count, maternal fever, maternal tachycardia, fetal tachycardia) we found CRP level to be more sensitive (100%) but less specific (45.45%) in identifying chorioamnionitis. The positive predictive value was 31.4% and negative predictive value was 100%.Conclusion: CRP is early and reliable indicator of histopathological and clinical chorioamnionitis in comparison of TLC and clinical parameter. Thus CRP can prove useful markers in identify early and subclinical infection which could lead to premature rupture of membrane.Key-words- Preterm birth, C-reactive protein, PPROM, Chorioamnionitis.

Wolf-Hirschhorn syndrome is a genetic condition that affects many systems of the human body. It is caused by a deletion of the band 4p16.3 and this deletion may be sub microscopic. Individuals affected by the syndrome have a special phenotype: wide bridge of the nose, widely spaced eyes, micrognathia, microcephaly, growth retardation, cryptorchidism, heart defects, hearing loss and severe intellectual disability. A familial translocation is seen in 5-13% of the patients. Other patients have de novo deletions, usually on the paternal chromosome 4, or de novo translocations in 1.6%. Prenatal diagnosis is possible. We are hereby reporting a case of 9 months old infant who showed delayed physical and neurocognitive development and a characteristic appearance, which led to the diagnosis of this genetic disease.

Bartholin’s gland cysts and abscesses are the most common cystic swelling of the vulva in women of reproductive age. These are usually small in size but the discomfort associated with it necessitates early consultations. Huge Bartholin’s abscesses are uncommon. Fewer cases have been reported among non-pregnant women. This case involved a 29-year old second gravida, who presented at a gestational age of 34 weeks with a vulval swelling measuring 8 x 8 cm, following failure of its resolution from self-medicated antibiotics. She had experienced similar but smaller vulvar enlargement in her previous pregnancy that had resolved following similar medical treatment. She was treated successfully with marsupialization, without any adverse effect on the pregnancy. This case shows the likelihood of huge Bartholin’s abscess complicating pregnancy and that there should be no hesitation to apply marsupialization in its treatment. The recurrence of the abscess in successive pregnancy in this woman, who kept using self-prescribed antibiotics, is a worrying trend and it requires educating women at various reproductive health care clinics about vulvar swellings and warns against antibiotics abuse. Key words: Bartholin’s abscess; marsupialization; pregnancy.