The enantioselective addition of aldehydes to diethyl azodicarboxylate in ionic liquids in the presence of chiral organocatalysts has been investigated. Of seven different organocatalysts tested, L-proline and L-thiazoline-2-carboxylic acid gave the highest enantioselectivities (up to 94 % ee).
Diethyl Azodicarboxylate. -The reaction is investigated in the presence of chiral organocatalysts. The best results are obtained using [bmim]BF4 and L-proline. -(KOTRUSZ, P.; ALEMAYEHU, S.; TOMA*, S.; SCHMALZ, H.-G.; ADLER, A.; Eur. J. Org. Chem. 2005, 22, 4904-4911; Dep. Org. Chem., Fac. Nat. Sci., Comenius Univ., SK-842 15 Bratislava, Slovakia; Eng.) -Bartels 10-140
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