Biphosphonate-related osteonecrosis of the jaw (BRONJ) is a common complication of the therapy of malignant cancers. Drugs improve bone density and reduce hypercalcaemia in patients with primary tumours, as well as their metastases to the bones. A characteristic feature are emerging foci of osteonecrosis of the jaws, with secondary infection which is often actinomycotic. Actinomyces are Gramm-positive bacteria which colonize the mucous membrane and in favourable conditions are the cause of inflammation. BRONJ appears spontaneously or may be a consequence of surgical treatment in the area of the jaws. The case is presented of an 82-year-old woman after hysterectomy due to a cancerous lesion who had taken ibandronic acid for a long time. Because of the severe pain in the mandible and the advanced disease, surgical sequestration of the necrosis and antibiotic treatment of the actinomycosis were necessary.

The presented case report concerns a patient with a foreign body in the orbital cavity-a fishing weight. After performing diagnostic tests, a multidisciplinary procedure was performed to remove the foreign body under general anaesthesia. Ophthalmologic consultation carried out after the procedure showed normal vision of the right and left eye. Penetrating foreign bodies of the orbit due to the variety of shapes and sizes, chemical composition and location, as well as potential serious consequences of such an injury require accurate diagnosis. This starts with determining the pathomechanism of the injury and selecting the appropriate radiological methods, and ends with a multidisciplinary approach to treatment.

Gorlin-Goltz syndrome (GGS) is a genetic disease of autosomal dominant inheritance. It is characterized by the presence of multiple basal-cell carcinoma foci, odontogenic keratocysts and anomalies of the skin, eyes, bones, nervous and endocrine system. Patients are predisposed to various neoplasms, such as medulloblastoma and fibrosarcoma. Rare incidence of the syndrome and multi-organ manifestations require providing patients with multi-specialist care, in particular, with dermatologists, dentists and surgeons. This is a case report of a 63-year-old patient with Gorlin-Goltz syndrome treated for odontogenic keratocysts of the mandible and basal-cell carcinoma. The report includes an extensive review of the GGS with regard to its etiology, features, clinical examination, diagnostic criteria and treatment modalities.