The rate of osteoporotic hip fracture was relatively low in southern Iran. However, by aging population, this rate will increase and health policy makers should implement targeted osteoporosis screening and management programs.

Background There are limited data on cardiovascular complications of coronavirus disease 2019 in pregnancy, and there are only a few case reports on coronavirus disease 2019 related cardiomyopathy in pregnancy. Differentiation between postpartum cardiomyopathy and coronavirus disease 2019 related cardiomyopathy in pregnant women who develop severe acute respiratory syndrome coronavirus-2 infection during peripartum could be challenging. Here, we present a case of possible coronavirus disease 2019 related cardiomyopathy in a pregnant patient, followed by a discussion of potential differential diagnosis. Case presentation In this case report, we present the case of a young pregnant Iranian woman who developed heart failure with pulmonary edema after cesarean section. She was treated because of low left ventricular ejection fraction and impression of postpartum cardiomyopathy, and her severe dyspnea improved by intravenous furosemide. On day 3, she exhibited no orthopnea or leg edema, but she was complaining of severe and dry cough. Further evaluation showed severe acute respiratory syndrome coronavirus-2 infection. Conclusions The possibility of severe acute respiratory syndrome coronavirus-2 infection should be considered in any pregnant woman who develops cardiomyopathy and pulmonary edema.

Objective: Helicobacter pylori infects at least 50% of the world’s human population. The current study aimed to assess and compare the efficacy of triple versus quadruple therapy. Methods: Randomized clinical trials (RCTs) consisting of triple and quadruple therapy were identified through electronic and manual searches in the national and international online databases (IsI, Magiran, Embase, PubMed, and Scopus). The random-effects model was applied to pool analysis. Funnel plots and the Egger test were used to examine publication bias. Results: After a detailed review of the selected articles, 79 RCTs were included in the meta-analysis; it was based on using triple and quadruple therapy as the first and second-line treatment. The results showed that quadruple therapy in the first-line treatment had a higher eradication rate than triple therapy. Overall, the eradication rate with triple therapy was 74% (95% CI, 71%-77%) for intention-to-treat (ITT) analysis and 80% (95% CI, 77%-82%) for per-protocol (PP) analysis. Generally, the eradication rate with quadruple therapy was 82% (95% CI, 78.0%-86.0%) for ITT analysis and 85% (95% CI, 82.0%-89.0%) for PP analysis. The analysis also revealed that quadruple therapy was more effective for 7 or 10 days. Conclusion: The current study results demonstrated that quadruple therapy has better effectiveness than triple therapy as the first-line treatment; however, in the second-line treatment, the effectiveness of quadruple and triple regimens is almost similar. The effectiveness of quadruple therapy in the Asian population was found to be slightly higher than that of triple therapy, while this difference was considerably higher in the European population.

Introduction Acinetobacter baumannii is an opportunistic pathogen that can cause hospital-acquired infections. Indiscriminate use of antibiotics has led to a significant increase in the incidence of acquired drug resistance among clinical isolates of A. baumannii. This study aims to assess the resistance to carbapenems between A. baumannii clinical isolates using a meta-analysis study. Methods The databases of Scopus, PubMed, Google Scholar, Web of Science, and Iranian national databases (SID, Magiran, and IranMedex) were searched until 2020. Studies were analyzed based on the random-effects model. Heterogeneity between studies was evaluated by calculating the I 2 index. Statistical analysis was performed using STATA (version 14.2; StataCorp, College Station, Tex). Results Finally, 46 articles were found to meet the criteria, with a total sample size of 62,779 cases. Resistance to imipenem and meropenem was detected in 62% and 64% of cases, respectively. The sensitivity of A. baumannii clinical isolates to imipenem and meropenem was obtained at 34% and 37%, respectively. In addition, the highest resistance to imipenem and meropenem was estimated in Asia (67% and 70%, respectively). However, the lowest resistance to imipenem and meropenem was estimated in Europe (50% and 57%, respectively). Conclusion The carbapenem resistance of A. baumannii is a global health problem that affects public health in the community. Based on our results, because of the high resistance of A. baumannii to carbapenems, the extensive use of carbapenems is less recommended.