Single fetal cardiac tumors and follow-up based on 13 cases from the Fetal Cardiac Referral Center in Prenat Cardio 2017 Jan; 7(1):43-49 DOI: 10.1515/pcard-2017-0007 INTRODUCTIONFetal cardiac tumors are rare anomalies: 0,08-0,2% 1,2, while data from Polish Nationwide Register of Fetal Cardiological Problems (in polish-ORPKP), suggested higher prevalence (1,05% Single fetal cardiac tumors are some sort of enigma and for now, there is no unitary algorythm of proceeding, that is why it become the aim of our work. MATERIALThe analysis included 13 cases from our unit Fetal Cardiology Department -Referral Center in the middle of Poland, during the years 1993-2017. Study group were women at the age of 18-37 years, average gestational age during targeted echocardiography examination was 34 weeks of pregnancy. The earliest registration of cardiac tumor was in 20th week of pregnancy, and the latest was during perinatal period (40th week of pregnancy).Corresponding author : a.b.zalinska@gmail.com Submitted: 2017-11-16; accepted: 2017-11-25 Results: Ten out of 13 fetuses with single cardiac tumors (SFCT) had cardiomegaly: on average HA/CA was 0,49. The size of the tumor was different: the smallest one -6 x 6 mm, the biggest 47 x 47 mm. The way of the delivery: in 10 cases there was CS and in 3 cases natural delivery. Birth weight was from 2000-3950 g (average 2989,2 g). Cardiosurgical resection of the tumor was performed on 4 newborns: at 2nd, 4th, 8th and 16th day of life (average 7,5 day). Four neonatal deaths were registered (31%): in 1st 2nd and 11th day (before surgery) and in the 28th day after the operation.Conclusions: Single fetal cardiac tumors (SFCT) can be diagnosed at 20 weeks of pregnancy, which allows to start echocardiographic monitoring, taking into consideration the potential risk of hemodynamic progression. SFCT can be the first sign of tuberous sclerosis complex in later prenatal or postnatal life. SFCT other than rhabdomyoma can be asymptomatic in newborn, but may require an early cardiosurgical resection.