Background: In light of the coronavirus disease 2019 (COVID-19) pandemic, cancer centres in the United Kingdom and Europe re-organised their services at an unprecedented pace, and many patients with cancer have had their treatments severely disrupted. Patients with cancer were considered at high risk on sparse evidence, and despite a small number of emerging observational studies, the true incidence and impact of COVID-19 in the 'at-risk' population of patients with cancer is yet to be defined. Methods: Epidemiological and clinical data were collected prospectively for patients attending the Royal Marsden Hospital and three network hospitals between March 1st and April 30th 2020 that were confirmed to have Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection. Significance of clinical and pathological characteristics was assessed using the Fisher's exact test and Wilcoxon rank sum test, whilst univariate and multivariate logistic regression models were used to further assess risk. The number of patients attending in March/ April 2020 for face-to-face attendances was also extracted. Findings: During the 2-month study period, 867 of 13,489 (6.4%) patients met the criteria leading to swab testing. Of the total at-risk population, only 113 of 13,489 (0.84%) were swab positive, 101 of 13,489 (0.75%) required hospital admission and 29 of 13,489 (0.21%) died of
Objetivo: Revisar a literatura com o objetivo de elucidar os principais tópicos relacionados ao Papilomavírus Humano (HPV) e analisar o impacto desta infecção na qualidade de vida dos pacientes. Revisão bibliográfica: Classifica-se o HPV como uma Infecção Sexualmente Transmissível (IST) de alta prevalência. Dentre os fatores de risco dessa etiopatogenia, pode-se destacar hábitos de vida e comorbidades, as quais diminuem a resistência imunológica e ocasionam o aparecimento de lesões intraepiteliais. Os portadores tendem a apresentar manifestações assintomáticas ou tardias, de forma que transmitem o vírus sem saber. Embora prevalente, o diagnóstico positivo apresenta impacto negativo na qualidade de vida dos portadores, devido ao preconceito social relacionado a este. Considerações finais: Portanto, nota-se que é fundamental a propagação de informação em massa sobre o HPV, com objetivo de induzir uma maior vacinação e, assim, prevenir lesões de alto risco e atenuar a prevalência deste vírus e os impactos do diagnóstico positivo.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.