The IIFF model of organ donation holds that the simultaneous presence of four factors directly influence donor registration: (1) immediate and complete registration opportunity (ICRO), (2) information, (3) focused engagement, and (4) favorable activation. Two field experiments examined the impact of an ICRO on organ donation registration. In Study 1, participants were at town halls where they knew organ donation was to be discussed. Registration cards were distributed and then collected at the end of the session in half of the town halls. For the other half, participants were asked to mail in completed cards. In three US cities, participants given an ICRO registered at a significantly greater rate (z = 4.865, p < 0.05). Study 2, targeting Hispanics at a swap meet, differed in that the registration impact of awareness of the availability of an ICRO was investigated. Participants made aware of an ICRO registered at a significantly greater rate (z = 4.1, p = 0.000).

There is little debate over Hispanics' need for viable organs. Although organ donor registries can potentially assist in alleviating this need, the U.S. Department of Health and Human Services (DHHS) has called on researchers to investigate methods to maximize such potential. This research effort answers the aforementioned call by surveying Hispanics, both those who prefer to use Spanish (SP, n=239) and those who prefer not to use Spanish (NSP, n=364) about the methods of donor registration that they would most likely utilize. When provided with different options for organ donor registration, signing up by applying for a driver's license, through a place of worship, or through a doctor's office were among the most popular methods; over the telephone, tax forms, or through the use of home computer were among the least popular. Furthermore, the DHHS-suggested idea of registering via organ donor kiosks was very well received.

The data provide a springboard for larger studies encompassing the diversity and geographical dispersion of Hispanic Americans. The data also highlight the importance of educational efforts to make Hispanic Americans aware of people in their community who have donated in the past or who are now potential donors.

When it comes to organ donation, the majority of American non-donors are passive-positives - they support organ donation but have yet to register as donors. A quasi-experimental, four-city, pretest/posttest study was conducted to assess the utility of the IIFF Model as a means of increasing registration among these individuals. Focus groups were used as the intervention context. In support of the model's utility, 46.6% of focus group participants signed donor cards at the end of the intervention. Extrapolated to the general population, such a finding could result in millions of new registrants. Retrospective analyses of reasons for non-registration provided before the start of the focus groups reveal that passive-positives placing culpability for non-registration on lack of knowledge or opportunity register signed-up at a rate of 63.6%. Passive-positives claiming to have put off registering because of their discomfort with thoughts of death or fear that organ donors are allowed to die so their organs can be harvested registered at a rate of 5.8%.

The findings from this study have implications for both organ donor investigations and health campaign research in general. Statistical interactions highlight the importance of evaluating multiple exemplars in multiple locations for each type of appeal when conducting health campaign research.