Despite a standard automated perimetry within normal limits, the StratusOCT detected both localized and diffuse RNFL thinning in PU eyes of glaucoma patients. These eyes should be considered at risk of developing functional damage over time and consequently require thorough monitoring for detecting any sign of progression.

Purpose: to compare the rebound tonometer ICare® (RT) with the Goldmann applanation tonometer (GAT) in cataract surgery and to assess the influence of central corneal thickness (CCT) on intraocular pressure (IOP) measurements. Design: retrospective, comparative study. Methods: a total of 472 patients underwent IOP measurement using RT (time 0 = RTa). GAT IOP measurement was performed 5 minutes later, followed by a second RT IOP measurement after other 5 minutes (RTa + 10 min = RTb). CCT was obtained by ultrasound pachymetry. In 106 patients IOP was measured by means of RT and GAT before clear corneal cataract surgery (RT1 and GAT1) and at one day postoperatively (RT2 and GAT2). Results: RT IOP values > 5 mmHg were overestimated, while RT IOP values < 15 mmHg were underestimated. Every 100 µm of CCT an increase of 0.97 mmHg and 0.33 mmHg was found for RT and GAT respectively. The difference between RT1 and RT2, GAT1 and GAT2, RT1 and GAT1 was not statistically significant; while the difference between RT2 and GAT2 was statistically significant (p < 0.04). The difference between RTa and RTb was not statistically significant whereas the difference between RTa and GAT and RTb and GAT was statistically significant (p < 0.001). Conclusion: our results showed a good agreement between measurements obtained with RT and GAT in pre and postoperative cataract surgery, although a significant statistically difference was found between RT and GAT measurements performed postoperatively. Moreover, CCT is a parameter to be considered for the IOP measurement, especially for values obtained with RT.

Purpose: To evaluate FDT Matrix 24‐2 threshold strategy diagnostic performance in discriminating healthy subjects from glaucoma suspects (GS) and ocular hypertensives (OH) patients. Methods: 23 healthy subjects, 27 OH, 21 GS and 20 EG patients were recruited. Classification was based on optic disc and Humphrey Field Analyzer (HFA) perimetry criteria (glaucoma if PSD<95% and/or GHT outside normal limits). A complete ophthalmologic evaluation, HFA (24‐2, SITA standard) and FDT perimetry (24‐2, ZEST strategy) were performed in all subjects. A severity score (from 1 for points with <5% probability up to 4 for probability <0.5%) was calculated from defective points on pattern deviation map and mean values (±SD) in the 4 groups were compared at Mann‐Whitney test. AUROC curves were created in order to assess MD, PSD and severity score diagnostic accuracy. Results: MD and PSD displayed chance discriminating power in OHs (AUROC<0.6) on both instruments. For GSs, FDT‐MD and PSD have larger but not statistically significant AUROC than HFA. For EG, diagnostic performance of the two instruments is very similar with excellent AUROC (>0.9). Severity score on the 2 instruments are similar for OHs, whereas significance limit was nearly reached (p=0.057) for GSs and significant difference appeared (p=0.002) for EG eyes with higher score on FDT. Conclusions: FDT Matrix 24‐2 threshold strategy apparently does not offer advantages over HFA in OH and EG. In GS, statistically significant improvement in diagnostic accuracy was not demonstrated, probably because of insufficient sample size. Thus, the role of FDT Matrix in clinical practice needs further investigation.