Purpose Total hip and knee arthroplasty periprosthetic joint infection (PJI) poses a management dilemma owing to the emergence of resistant organisms. A promising option is Bacteriophage therapy (BT) was used as an adjuvant for PJI management, aiming at treating resistant infections, decreasing morbidity, and mortality. The current review aimed to demonstrate the role and safety of using BT as an adjuvant to treat PJIs. Methods A systematic search was performed through four databases (Embase, PubMed, Web of Science, and Scopus) up to March 2022, according to the predetermined inclusion and exclusion criteria. Results Our systematic review included 11 case reports of 13 patients in which 14 joints (11 TKAs and three THAs) were treated. The patients’ average age was 73.7 years, underwent an average of 4.5 previous surgeries. The most common organism was the Staphylococcus aureus species. All patients underwent surgical debridement; for the 13 patients, eight received a cocktail, and five received monophage therapy. All patients received postoperative suppressive antibiotic therapy. After an average follow-up of 14.5 months, all patients had satisfactory outcomes. No recurrence of infection in any patient. Transaminitis complicating BT was developed in three patients, needed stoppage in only one, and the condition was reversible and non-life-threatening. Conclusion BT is a safe and potentially effective adjuvant therapy for treating resistant and relapsing PJIs. However, further investigations are needed to clarify some BT-related issues to create effective and reproducible therapeutics. Furthermore, new ethical regulations should be implemented to facilitate its widespread use.

Background The scientific activity of an institution or an individual researcher is being measured through various indicators; of which is their amount or publication and citation. Inappropriate presentation or reporting of the authors' affiliation may deprive their institution of getting the research credit for the published work. The study primary objective was to detect the possible patterns of authors' affiliation misreporting by evaluation Qena Faculty of medicine (QFM) (as a representative of Egyptian academic institutions) PubMed indexed publications over one year period. The Secondary objectives were to, 1: document the QFM contribution to the South Valley University (SVU) publications and 2: to check the incidence of contribution from QFM different departments through the same period. Results A PubMed search limited to one year searching for publications from SVU, QFM and QUH. The resulted articles were examined to evaluate the contribution of different faculties to the overall SVU publications. QFM and QUH were further evaluated for, contribution of the departments, and the presence of authors affiliation misreporting, the later was divided into three main patterns, Ⅰ: Missing affiliation information, Ⅱ: Mistakes in affiliation reporting, and Ⅲ: Inconsistent affiliation reporting. A total of 261 articles were examined. Faculty of Veterinary Medicine was the most contributing by 95 (35.2 %) articles followed by QFM by 77 (28.4 %). For the 77 articles published from QFM and QUH, the cooperation between QFM departments was as follows: authors from only one department (59, 76.6%), two (9, 11.7%), three (4, 5.2%), and four (5, 6.5%), this makes a total contribution of all departments as 105 articles, of which 83.8% and 16.2% from clinical and academic departments respectively. The most commonly occurring authors affiliation misreporting was pattern Ⅱ in 47 (44.8 %) articles, followed by pattern Ⅲ in 31 (29.5%) pattern and pattern Ⅰ in 16 (15.2%). Conclusions Certain patterns of authors' affiliation misreporting were detected; identifying such patterns will help avoid them in future and to guard against depriving a certain institution of its research credit. Further evaluation of other faculties or universities on a wider scale is highly encouraged.

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Evaluation and interpretation of an electrocardiogram (ECG) is not formally included in the surgical residencies teaching curriculum, at least in our area. In this review, we aimed to discuss some of the basic ECG principles that could enable an orthoapedic surgeon to perform an initial assessment of an ECG trace paper and report on the ECG appearance of some common postoperative cardiovascular complications. Some reports have been published about surgeons' capability in dealing with an ECG trace paper. Since a subset of patients going under different surgical procedures being old and fragile with more susceptibility to postoperative cardiovascular complications, even in the absence of a history of cardiovascular comorbidity. Having the necessary knowledge regarding ECG assessment, a surgeon could suspect or diagnose these complications. In this review, we explained the basic concepts of cardiac electrophysiology, the typical components of an ECG trace paper, and a systematic approach to interpreting. We provided some of the commonly encountered postoperative cardiovascular complications and their appearance in the ECG trace paper. As we believe that orthoapedic surgeons should master basic ECG interpretation skills, this review will serve as an opportunity and a guide to understanding the essential components and concepts of an ECG trace paper.