The target-oriented synthesis of the active diastereomer of pyranoquinoline (IV) presented, circumvents the problem of effective separation of diastereomers and completely rules out the risk of contamination by the inactive diastereomer (IV) thus ultimately reaching the maximal bactericidal and bacteriolytic effects. Related furanoquinoline (VII) can be obtained with similar diastereoselectivity. -(MAGESH, C. J.; MAKESH, S. V.; PERUMAL*, P. T.; Bioorg. Med.
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