Renal transplant recipients receiving immunosuppressive therapy are prone to major pulmonary infections. Development of influenza virus infection may lead to renal allograft damage or rejection. These patients should therefore be protected against influenza viruses by vaccination. A satisfactory antibody response was found in 12 (60%) of 20 renal transplant recipients vaccinated. Among 15 control subjects, the antibody response was satisfactory in all participants (100%). Factors that might play a role in suppression of antibody response include use of immunosuppressive drugs and renal allograft function. Immunization is safe and does not appear to affect renal allograft function.
Laparoscopic cholangiography is invaluable in the detection of bile duct stones, visualization of ductal anomalies and discovery and prevention of iatrogenic injuries to the bile ducts. The use of this procedure is, however, limited by the technical difficulties of cystic duct cannulation. A method of laparoscopic cholangiography that avoids cystic duct cannulation is described. It consists of a Kumar I Cholangiography Clamp that is applied across the gallbladder just above the Hartmann's pouch and divides the gallbladder into a medial and lateral compartment. A Kumar Cholangio Catheter is then introduced through the side-channel of the clamp, puncturing the medial compartment (i.e. the Hartmann's pouch) with a short #22 gauge needle for aspiration, followed by dye injection. Cholangiography was obtained with remarkable ease in 49 of the first 50 cases (98%) without complication.
Embryonic Mortality is the major cause of reproductive and economic loss in cattle and Buffaloes. Embryonic Mortality is more common during the early than the late embryonic period, i.e., from day 8th to 16th at the hatching of blastocysts and initiation of elongation and commencement of implantation without affecting cycle lengths. Early embryonic mortality is a major source of embryonic and economic loss with mortality rate up to 40%. Embryonic mortality is also reported due to mineral deficiency and heat stress in cattle and buffaloes. Physical modifications of animal environment, nutritional management with Antioxidant, trace minerals and genetic development of breeds that are less sensitive to heat stress should be best solution. Embryonic death occurs at the time of maternal recognition of pregnancy, probably related to a failure of the Interferon tau (IFNι) secretory mechanism along with progesterone deficiency and luteal insufficiency. Recent research, both in terms of physiological mechanisms and pharmacological treatments has mostly focused on the period of maternal recognition of pregnancy or the anti-luteolytic effect. hCG/ GnRH /Progesterone supplementation have shown positive results. Supplementation of interferon as anti-luteolytic agent and supplementing Omega-3 has shown encouraging results. Ovarian examination, Animal history, blood/milk progesterone levels, PAG test and ultrasound appear to be the only practical tool presently available for diagnosis of embryonic mortality. This present review article is covering all the aspects of embryonic mortality with special reference totrace minerals, heat stress, hormonal impact and interferon tau.
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