Abstract.A study using one group pre-post-test experimental design on Life organization system topic was carried out to investigate student's tendency in learning abstract concept, their creativity and collaboration in designing and producing cell models through STEM-based learning. A number of seventh grade students in Cianjur district were involved as research subjects (n=34). Data were collected using two tier test for tracing changes in student conception before and after the application of STEM-based learning, and rubrics in creativity design (adopted from Torrance) and product on cell models (individually, in group), and rubric for self-assessment and observed skills on collaboration adapted from Marzano's for life-long learning. Later the data obtained were analyzed qualitatively by interpreting the tendency of data presented in matrix sorted by gender. Research findings showed that the percentage of student's scientific concept mastery is moderate in general. Their creativity in making a cell model design varied in category (expressing, emergent, excellent, not yet evident). Student's collaboration varied from excellent, fair, good, less once, to less category in designing cell model. It was found that STEM based learning can facilitate students conceptual change, creativity and collaboration.

This research is motivated by the low ability of mathematical critical thinking and Self Regulated Cimahi 10 Public Middle School students, so that a learning approach is needed to overcome these problems. The alternative approach applied is the Brain Based Learning Model approach.The objectives of this researcher are: 1) to examine students' mathematical critical thinking skills; 2) reviewing the Self Regulated attitude of students who obtain Brain Based Learning learning with students who have expository learning; 3) examine there is a positive correlation between Critical Thinking with Self Regulated students who obtain Brain Based Learning and expository learning. The population in this study was grade VII students of SMP Negeri 10 Cimahi. The samples in this study were class VII-B (Brain Based Learning) and class VII-D (expository). The instruments used in this study were the Critical Thinking test and the student's Self Regulated questionnaire. The test used is a subjective type test (description). The way to analyze data is with IBM SPSS Statistics 18.0 for Windows. The results showed that: 1) the mathematical critical thinking ability of students who obtained learning based on the Brain Based Learning approach was better than students who gained expository learning; 2) Self Regulated  attitude, students who get Brain Based Learning are better than students who get expository approach learning; 3) there is no correlation between critical thinking with Self Regulated students who obtain Brain Based Learning and expository learning.