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The presence of periodontal bacteria DNA in coronary atheromatous plaques and sub-gingival plaque samples of the same patients was confirmed by this study. CONCLUSION A correlation was established between putative bacteria contributing to atheromatous plaques and species associated with periodontal disease. One particularly important study to be carried out is the investigation of a possible clinically meaningful reduction in coronary heart disease resulting from the prevention or treatment of periodontal disease.

Quantum structures were fabricated by immersing a crystalline silicon (Si) or germanium (Ge) wafer in hydrofluoric acid followed by laser‐induced etching with a laser photon energy of 2.41 eV. Atomic force microscopy (AFM) investigations of Si(100) etched samples reveal a complex surface morphology with pits from the top view and pillar‐like structures from the three‐dimensional view of the pit wall. For Ge(111) laser‐etched samples, AFM shows parallel wall‐type structures and Ge quantum structures on the surface of the walls. Laser‐induced etching of Ge is reported for the first time. Observation of photoluminescence spectra from both samples confirms the presence of quantum confined structures. Line‐shape analysis of Raman spectra is used to estimate the size of the quantum structures. The sizes of nanoparticles can be controlled by the laser power density and irradiation time for etching. (© 2006 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

BackgroundAcute myeloblastic leukaemia is a malignant bone marrow neoplasm of myeloid precursors of white blood cells. Due to its high morbidity rate, early diagnosis and appropriate medical therapy is essential.MethodsThe article highlights normal blood alterations like anaemia, thrombocytopenia, leukocytosis and advanced diagnostic aids like flow cytometry, special staining as a diagnostic modality as well as for prognostic information in acute leukaemia, particularly as a tool for assigning lineage and facilitating further pathologic classification which may be helpful in influencing treatment strategies.ResultsOn clinical examination the case presented with features of inflammatory gingival enlargement with presence of local deposits and calculus. Routine blood examination anaemia, thrombocytopenia, leukocytosis with haemoglobin 5.6 gm% and total leukocyte count of 1,12,000 / cu mm suggestive of leukaemia. Myeloperoxidase and leukocyte nonspecific esterase (NSE) special stain were used which showed presence of myeloblasts in the peripheral smear suggestive of acute myelocytic leukaemia. Flow cytometry were done which further helped in interpretation of these cells which showed to be strongly positive for CD45, CD13, CD14, and anti HLADR and moderately positive for CD4, CD34 and Anti MPO confirming to be case of AML-M4 with 57.73% gating.ConclusionsFact that gingival alterations are sometimes the first manifestations of the disease implies that dental professionals must be sufficiently familiarized with the clinical manifestations of systemic diseases. The timely referral by the general dentist for a suspicious lesion provided an early diagnosis and early intervention reducing the patient morbidity.