It is crucial to understand the various biological effects induced by terahertz (THz) electromagnetic waves with the rapid development of electronic and photonic devices operating in the THz frequency region. The presence of sweat glands plays an important role in THz wave interactions with human skin. We investigated the morphological features of sweat ducts using optical coherence tomography (OCT) to further understand such phenomena. We observed remarkable features of the ducts, such as their clear helical structure. The intersubject and intrasubject variations in the diameter of sweat ducts were considerably smaller than the variations in other structural parameters, such as length and number of turns. Based on the sweat duct dimensions and THz dielectric properties of skin measured using terahertz time-domain spectroscopy (THz-TDS), we calculated the resonating frequency of the sweat duct under the assumption of it functioning as a helical antenna. Here, we show that the resonance frequency in the axial mode of operation lies in the THz wave region with a centre frequency of 0.44 ± 0.07 THz. We expect that these findings will further our understanding of the various health consequences of the interaction of THz waves with human beings.

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In 2003, we reported the first-ever development of a spectral imaging system for illicit drugs detection using a terahertz (THz) wave parametric oscillator (TPO) [K. Kawase et al., Opt. Exp. 11(20), 2549 2003]. The system has a dynamic range below four orders of magnitude, which enables it to identify reagents only through thin envelopes using spectral imaging. Recently, we succeeded in developing a high power and high sensitivity THz wave spectral imaging system using injection-seeded THz parametric generation and detection. A dynamic range in excess of 80 dB has been obtained, which is much higher than that of the 2003 system. In this study, the new spectral imaging system successfully identified reagents through thicker material than the thin envelopes used previously.

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