Keratoacanthoma (KA) is a case related to skin squamous cell carcinoma but it is a selflimited case. It is usually seen in areas of exposed skin and rarely to be seen intra-orally. Here we present a case of oral keratoacanthoma on the alveolar ridge of the maxillae, which may arise as a result of trauma or unknown stimulus. The case was treated with liquid nitrogen for six sessions and completely resolving of the lesion was recorded without a scar formation. Cryosurgery for exophytic lesions either benign or malignant (well differentiated) is worthy to be recommended than traditional surgery.