The formation of conglomerate salts from chiral molecules, which crystallize as racemic compounds, expands the theoretical application range of Viedma Ripening roughly 10 fold. In the present study, on the use of conglomerate forming salts was studied for temperature cycling, an alternative technique for Viedma ripening. The racemic compound Phenyalanine (Phe) was successfully deracemized via its conglomerate-forming salt with 2,5-xylenesulfonic acid (XSA) by continuous heating-cooling cycles applied to its suspension in glacial acetic acid, coupled with a solution racemization reaction. In addition, the dependence of the deracemization rate on the operational parameters was studies. The results can be used as guidelines for process optimization as well as for the understanding of the mechanism behind temperature cycling. The advantages and disadvantages of temperature cycling and Viedma Ripening, as deracemization methods in an industrial setting are discussed.