21Quantitative assessment of antibiotic-responsive RNA transcripts holds promise for a 22 pump alleles acquired from commensal Neisseria, three resistant isolates with the C2611T 23s 126 rRNA mutation, and one resistant isolate with the A2059G 23s rRNA mutation (17, 18). A total 127 of ~258 million 50 bp paired-end reads were generated across 90 libraries. Each library had on 128 average 3.17 ± 0.16 million reads, and an average of 1.82 ± 0.11 million reads per library 129 mapped to the FA1090 (AE004969.1) reference genome. 130 131 Genetic distance and population structure impact transcriptome regulation 132