High quality P‐doped Zn1‐xMgx Te crystals with Mg composition x of 0.09 to 0.3 were grown by vertical Bridgman method. The typical value of the full width at half maximum of (004) X‐ray ricking curve was 65.7 arcsec. For the first time temperature dependence of photoluminescence measurement were successfully attained by using the P‐doped Zn1‐xMgx Te crystals. All the crystals showed not only excitonic emission with no donor‐acceptor pair emission at low temperature but also photoluminescence (PL) band originated from interband transition at room temperature. From the temperature dependent PL intensity of free‐to‐bound (FB) transition emission, the relationship between x and the energy of P acceptor level was estimated by the use of one‐step model of thermal quenching mechanism. The result showed that the acceptor level monotonically increases with increasing x. This relationship seems to be reasonable which was supported by comparison with the energy difference between the peak of FB emission and estimated band gap at 4.2 K. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)

A 5-year-old girl had a caudal appendage and her left buttock was larger than the right buttock. X-ray examination revealed spina bifida and bony defect of sacrum; computed tomography demonstrated the extension of the tumor from subcutaneous tissue to the spinal canal. Histologically, the pseudotail contained lobulated fatty tissue which was consistent with lipoma. It emphasizes the fact that even lesions that are not situated in the median line should be carefully explored before excision.

Summary This study regards the urinary protein of patients with renal diseases. Analysis was done by micro‐vertical‐electrophoresis using polyacrylamide gel with sodium dodecyl sulfate (SDS‐PAGE). This method was an easy, reliable and rapid method for the estimation of low molecular weight proteinuria, which are present in renal tubular dysfunction. We found 6 patients with renal tubular dysfunction in 214 patients with renal diseases by the use of this method. Thus, the present method is considered to be useful for mass‐screening of children with proteinuria.

We report a case of double trisomy, 48, XXX, + 18 in a newborn female who had low set ears, prominent occiput, receding chin, overlapping fingers, structural heart disease and other malformations. These deformities are similar to the characteristic manifestations of trisomy 18 syndrome. She died on the 10th day. Autopsy revealed VSD, ASD, PDA, coarctation of the aorta, Meckel's diverticulum and cerebellar hypoplasia. Our case showed unilateral anomalies on the right side. These may help to suggest the diagnosis of double trisomy.

Urinary organic acid and acylcamitine profiles from a 2‐month‐old boy were studied by gas chromatography‐mass spectrometry and fast atom bombardment mass spectrometry. The patient excreted large amounts of glutaric acid and significant amounts of 3‐hydroxyglutaric acid, glutaconic acid and glutarylcarnitine, and his serum glutaric acid level was markedly elevated. Thus he was chemically diagnosed as having glutaric aciduria type I (GAI). In addition to the above metabolities previously described in GAI, significantly increased excretion of 2‐ketoglutaric acid, succinic acid, adipic acid, adipylcarnitine, suberic acid and azelaic acid was found. 2‐Ketoadipic acid methylsuccinic acid and ethylmalonic acid were also detectable, suberylcarnitine was not increased, and dehydroadipylcarnitine was decreased in his urine. These results suggest that excess glutaryl‐CoA causes the competitive inhibition of the dehydrogenation of adipylCoA to dehydroadipyl‐CoA and results in an increase of adipic acid and adipylcarnitine and a decrease of dehydroadipylcamitine. It is also suggested that oxidative decarboxylation of 2‐ketoglutaric acid to succinyl‐CoA is inhibited by high levels of glutaryl‐CoA, and that the dehydrogenation of succinic acid to fumaric acid is inhibited owing to the increased glutaric acid derived from excess glutaryl‐CoA. These results indicate that gas chromatography‐mass spectrometry is the most appropriate and accurate method for the differential chemical diagnosis of GAI and glutaric aciduria type II.