Neonatal purpura fulminans is a rare but frequently fatal disorder associated with high morbidity and mortality. Purpura fulminans describes a clinico-pathological entity of dermal microvascular thrombosis associated with disseminated intravascular coagulation (DIC) and perivascular hemorrhage occurring in the newborn period. It is usually congenital as a result of deficiency of protein C and S. it maybe be either idiopathic or acquired due to severe infection by gram negative organisms or Staphylococcus species. Here we present the case of a neonate born to an HIV reactive mother who presented to us at 6th day of life with desquamation of skin in periumbilical area which gradually progressed to involve the limbs, trunk as well as face. The neonate was managed with supportive therapy in ICU but despite intensive management, she expired at 10 days of life due to septicaemia and multi-organ failure.
Pleural effusion occurs when a large amount of free fluid accumulates in the pleural space. A chylothorax is caused by chyle-containing lymphatic fluid draining into the pleural cavity. This is the most common type of pleural effusion observed during the neonatal period. It causes a number of respiratory and nutritional issues and has a significant mortality rate. It is usually treated by intercostal chest tube drainage and total parenteral nutrition. Octreotide is a relatively newer strategy in the management. Here we describe the case of a 16 days old male neonate who presented to us with sudden onset severe respiratory distress requiring invasive ventilation. Radiology suggested pleural effusion and so intercostal chest tube was inserted, which revealed Chylous effusion. The patient was successfully managed with dietary therapy including skimmed milk and octreotide infusion.
One cannot think of a better way of introducing the concerns of Kamala Das- than by, quoting from her autobiography - My Story. “Poets, even the most significant of them are different from other people. They cannot close their shops like shop men and return home. Their shop is their mind and as long as they carry it with them; they feel the pressure and the torment.” (MS, 165). Reading Kamala Das’s works have been like journeying through a land that has its share of flood and famine, of lush green gardens and cold graves and scorching sun and rain bow skies, such is the harvest of thought in her work. Her works take leap from love to life, to death with the adeptness of an ace sprinter and the peculiar charm lies in how she manages love and life with the same intensity that she employs to celebrate them.
The problem of secure data transmission on cloud environments is addressed in the proposed security model. The data security is quite important on cloud environments because they belongs the users. The security layer is defined or implemented between the cloud user and server end to ensure the security of data being exchanged between them. In this research, a key exchange scheme has been proposed to ensure the security of cloud platforms. The proposed model under this research project presents improved random key management architecture, which may be called efficient multi-level complex key sharing and authorizing model (EMCKS) for the cloud platforms. In particular, the proposed model allows only authorized applications and/or users to use the keys. Using simple devices, administrators can remotely issue authenticated commands to EMCKS and verify system output. In this research, we will develop the proposed scheme named EMCKS for corporate key management technique adaptable for the clouds by making it efficient and quicker. In addition, it also has to be improved to work with Cloud server and client nodes, which enforces the proposed scheme to create a secure environment based cloud platforms. The proposed scheme has been noticed providing hardened security than the other key management architectures as it is based on non-predictive key generation mechanism. The results have shown the effectiveness of the proposed model in terms of elapsed time.
Tuberculosis (TB) continues to be a prevalent disease worldwide; according to World Health Organization (WHO), children and young adolescents represent about 11% of all people with TB globally. Although TB often is cited as a disease that commonly occurs in underdeveloped countries, the evolution of drug-resistant forms of TB and infection sensitivity of immunocompromised individuals have made this disease as a focal point for developed countries as well. Although pulmonary TB is the most common form worldwide, but TB can infect any organ of the body. An uncommon version- cutaneous TB- affects <2% of all individuals with active form of TB. This case report describes a 4-month-old child who presented to us with abdominal wall cellulitis following a history of fall related injury. Incision and drainage of the pus from the fluctuant area grew acid fast bacilli on Zeihl-Neelsen staining. After the child didn’t show any improvement with intravenous antibiotics, empirical anti-tuberculosis therapy was initiated after which there was marked improvement. Cutaneous TB constitutes a very small percentage of extra-pulmonary tuberculosis and is rarely seen in paediatric age group.
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