[reaction: see text] Pyridinium hydrobromide perbromide (Py x HBr3) catalyzes effectively the aziridination of electron-deficient as well as electron-rich olefins using Chloramine-T (N-chloro-N-sodio-p-toluenesulfonamide) as a nitrogen source to afford the corresponding aziridines in moderate to good yields.

A single step conversion of aromatic aldehydes (1) into the corresponding nitriles (2) has been achieved in high yields using stoichiometric amounts of hydroxylamine hydrochloride, pyridine and formamide in refluxing xylene.

nitriles nitriles (benzene compounds) Q 0520 -098Formamide Assisted One-Pot Conversion of Aromatic Aldehydes into the Corresponding Nitriles.-The title reaction fails with aliphatic aldehydes. It is noteworthy that aldoximes also undergo dehydration with formamide in xylene under reflux. Other solvents such as CHCl 3 or MeOH give low yields. -(ALI, SAYYED ILIYAS; NIKALJE, MILIND D.; DEWKAR, GAJANAN K.; PARASKAR, ABHIMANYU S.; JAGTAP, H. S.; SUDALAI, A.; J.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.