Monkeypox virus disease is a rare zoonosis that until recently was limited to Central Africa. We describe the clinical features of the third child in the United States reported with this newly emerging infection. This child was part of a large cluster of individuals in the Midwest infected by prairie dogs that had contracted the virus when housed with infected small mammals imported from Africa. The differential and laboratory diagnoses and the difficulty finding physicians and nurses to care for this patient are discussed.

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Herpes gladiatorum may cause substantial morbidity among wrestlers, and it is primarily transmitted by direct skin-to-skin contact. Prompt identification and exclusion of wrestlers with skin lesions may reduce transmission.