Cornus walteri Wanger (Cornaceae) has been broadly used in traditional East Asian medicine for the treatment of various disorders, including skin inflammation and diarrhea. As part of our efforts to identify structurally and/or biologically new compounds from Korean medicinal plants, we have explored potentially new bioactive constituents from C. walteri. In the present study, seven triterpenoids (1–7) were isolated from C. walteri stems and stem bark. Compounds 1–3 were new tirucallane triterpenoids (cornusalterins N-P) and compounds 4–7 were isolated for the first time from C. walteri. The structures of the new compounds were determined based on 1D and 2D NMR spectroscopic data interpretations and HR-ESIMS, as well as a computational method coupled with a statistical procedure (DP4+). The regulatory effects of the isolated triterpenoids (1–7) on mesenchymal stem cell (MSC) differentiation to adipocytes and osteoblasts were examined in the C3H10T1/2 cell line. Although these compounds had little effect on MSC differentiation to osteoblasts, lipid droplet formation in adipocyte-differentiated MSCs decreased in the presence of the seven triterpenoids. Compounds 1 and 4 each had a relatively distinct correlation between dose and efficacy, showing adipogenesis suppression at higher concentrations. Our findings demonstrate that the active compounds 1 and 4 can exert beneficial effects in regulation of adipocyte differentiation.

In this study, we studied on the durability of restorative cement mortar for deteriorated concrete at complex deteriorated conditions as variation of temperature and of humidities. We made a comparison between restorative materials with insulation function and restorative materials without insulation function in items of compressive and bending strength and permeability of water, durability for carbonation, salt damage, diffusion coefficient of salt at complex deterioration conditions like change of temperature, change of humidity, For insulation, we used close-pore type Alumino-Silicate lightweight aggregate and substituted 12 wt% and 15 wt% out of original restorative cement mortar without insulation function.As a result, it was found that original restorative cement mortar without insulation function fail to meet Korean Standard on polymer modified cement mortar for maintenance in concrete structure, but restorative cement mortar with insulation function is in contentment Korean Standard to meet excellent than restorative materials without insulation function for durability at complex deteriorated conditions.

Turbocharging is widely used in diesel and gasoline engines as an effective way to reduce fuel consumption. But turbochargers have turbo-lag due to mechanical friction losses. Bearing friction losses are a major cause of mechanical friction losses and are particularly intensified in the lower speed range of the engine. Current turbochargers mostly use oil bearings (two journal bearings and one thrust bearing). In this study, we focus on the bearing friction in the lower speed range. Experimental equipment was made using a drive motor, load cell, magnetic coupling, and oil control system. We measured the friction losses of the turbocharger while considering the influence of the rotation speed, oil temperature, and pressure. The friction power losses increased exponentially when the turbocharger speed increased.