The ancient literature of traditional Indian medicine indicate the potential medicinal values of Gmelina arborea as an important source of chemicals of enormous medicinal and pharmaceutical importance such as flavonoids, alkaloids, arboreol, isoarboreol, methyl arboreol, gummadiol, gmelanone, gmelinol, hexacosnol, n-octanol, β-sitosterol and luteolin. The present research has been undertaken with the aim to formulate and evaluate the herbal gel containing Gmelina arborea ethanolic leaf extract for antimicrobial properties. Phytochemical screening of Gmelina arborea reveals the presence of carbohydrates, alkaloids, saponins, tannins, anthraquinones and cardiac glycosides. The gel was prepared by using ethanolic leaf extract, Carbapol 934, methyl paraben, propyl paraben, propylene glycol, disodium EDTA, ethanol, triethanaloamine and distilled water. The physiochemical parameters of formulations such as pH, viscosity, spreadability and extrudability were determined. The results showed that the GF1 gel has better gel properties than other formulations. Determination of antimicrobial activity using the agar diffusion method showed that the crude extracts of the leaf and herbal gel of the plant inhibited the growth of recalcitrant pathogenic Staphylococcus aureus that frequently shows up in common skin infections. Neat ethanol extracts had the lowest minimum inhibitory concentration (MIC) of 0.01 μg each implying greatest activity against Staphylococcus aureus. Activity of the extracts was consistently less than the conventional antibiotic, tetracycline. Results provided the scientific basis for the folkloric application of G. arborea leaf extract for the possible control of skin infection associated with Staphylococcus aureus bacteria.

Artificial dyes, widely used in everyday items, come with side effects not known to the common man. They are toxic, harmful & mostly carcinogenic. There has been a worldwide increase in the demand of natural dyes due to its therapeutic properties & no known side effects. The current research aimed at extracting dyes of different colors from natural plant sources, carrying out its characteristic analysis & its applications. The dyes were tested for their anti-microbial ability and were found to be inhibitory to common organisms like S. typhi, C. diphtheriae, S. aureus, etc. Phytochemical tests were performed and they confirmed presence of several important metabolites like Phenols, Tannins, Terpenoids, and many more. The dyes were tested for anti-oxidant activity using the FRAP assay and antioxidant levels ranging from 0.62 to 2.00 were obtained. Preparations of cosmetics like lip balms, was carried out, and dyes were also tested as natural food coloring agents. The results indicated that the dyes caused inhibition of wide range of bacteria and proved to be good sources of anti-oxidants. They departed a natural color to food items and hence can replace artificial food colorings. Thus the use of natural dyes should be promoted, as they are cheap, biodegradable and feasible.

Pyoverdine, a fluorescent siderophore that have high- affinity for iron is produced by Pseudomonas putida and Pseudomonas aeruginosa that synthesizes it under iron-deficient growth conditions. Pseudomonas species are often encountered in diverse ecological habitats along side being censurable for nosocomial infections spread round the world. Due to these characteristics, there's a growing interest during this microbe for a spread of uses. One such is the production of Pyoverdine, it influences the uptake of iron, along with eliminating the limited iron availability condition. Pyoverdine is important for Pseudomonas putida and Pseudomonas aeruginosa to cause acute infections. Intense research and study led to the invention of Pyoverdines being a crucial source of chelating Iron. This study is predicated on Pyoverdine extracted from two different species of Pseudomonas which will act as an antimicrobial agent for various species including Escherichia coli and Staphylococcus aureus. The organism, i.e., Pseudomonas putida and Pseudomonas aeruginosa, were isolated from soil sample using medias like: Cetrimide media, King’s B media. It had been confirmed using primary biochemical tests, along side species level identification (MALDI - TOF). Isolation was followed by studying the antimicrobial activity of Pyoverdine on different organisms using antibiotics as standard for the same. Results for the tests were obtained, colonies were observed on specific media and zone of inhibition was observed on Muller Hinton plate. Comparative studies were carried out to find which organism used up Pyoverdine or Pyoverdine - Fe complex without using FeCl3 as sole standard source. Thus, these compounds can synergize with conventional antimicrobials, forming a simpler treatment with serving as a useful gizmo

Malignant cells multiply and divide uncontrollably in a variety of disorders known as cancer. These cells form tumors which are cancerous growths. There are various treatment available for cancer, still Ayurveda plays significant role. Ayurveda may be beneficial in the prevention, palliation, treatment, and support of cancer in a variety of ways. Ayurvedic medicine helps to raise living standards. It can be used in conjunction with chemotherapy or radiation therapy as an adjuvant or co-therapy. Ayurvedic treatment minimizes toxicities of chemotherapy and radiotherapy. In case of recurrence Ayurveda maintenance therapy will be helpful.

Antibiotic use in India has risen sharply, with about a 30% increase in their per capita use during the past decade. There is a significant amount of antibiotic abuse, self-medication, myths, and so on among the locals, which has led to the global problem of antibiotic resistance. As a result, the aim of this study was to assess the general public's level of knowledge and general awareness about antibiotics and its resistance. Questionnaire was designed as per our aim and was circulated randomly between 11th of February, 2021 and the 4th of March, 2021. The responses provided in the spreadsheet were later classified based on the demographic factors considered in our analysis. Later, feedback for proper practices was sent via email to their provided email address. Response rate: 95% (n=380/400) was achieved. According to the outcomes we obtained, the majority of respondents (290 out of 380) had learned of an antibiotic from a doctor or other medical professional. When asked to choose antibiotics from a list of medications, the Science stream had a higher proportion of correct responses. A substantial portion of the population had the misconceptions that taking antibiotics would weaken their bodies (n=142/380) or that antibiotics could differentiate between beneficial and harmful bacteria (n=136/380). The majority of allergies in the general population were caused by Sulpha-containing antibiotics, accounting for 55% of all allergy cases. According to the report, more than half of the population, or 69%, decided to discontinue after experiencing side effects. Respondents were asked if they knew about the antibiotic resistance to evaluate whether they are having the correct knowledge. Out of n=380 respondents, n=273 chose the correct choice. When asked whether acne medication causes resistance, only 19% chose the correct response, i.e. ‘Yes.' When asked about their views on preventing antibiotic resistance, n=244/380 responded to 'Safe food consumption and preparation,' n=152/380 responded to 'Know the signs,' and n=160/380 responded to 'Prevent infections’, all of which are right practices. Considerable part of the population is unaware about the antibiotic resistance problem which is now a global issue. Substantial part of the population is unaware about the practices to be followed to control this problem. Hence, there is dire need to spread awareness regarding the same.