Our results suggest that preventive measures, such as regular veterinary care for animals and educative and supportive activities oriented to the people working in farming and animal husbandry should be taken to decrease the prevalence of human CE in Turkey.

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ÖZAmaç: Primer rubella, sitomegalovirüs ve toksoplazma enfeksiyonu gebelikte ciddi komplikasyonlara neden olabilmektedir. Çalışmamızın amacı, Muğla ilindeki gebe kadınlarda rubella, sitomegalovirüs, toksoplazma, hepatit B virüsü, hepatit C virüsü ve HIV prevalanslarını belirlemektir. anti HBs pozitif idi. Anti HCV seropozitivitesi 1 gebe (%0,3) tesbit edilirken, anti HIV pozitif olan gebe tesbit edilmedi. Sonuç: Toksoplazmozisle enfekte fetüsün ve yenidoğanın ilk yılında tedavi edilmesinin klinik sonuçları iyileştirdiği bilinmektedir. Dolayısıyla toksoplasmozisin serolojik taraması hastalığı önle-me, tanı ve fetüsün erken tedavisinin sağlanmasında mevcut en güvenilir stratejidir. Rubella taramasının gebelik öncesinde yapılması önerilmeli ve seronegatif kadınlara aşı tavsiye edilmelidir. HBsAg taramasının, aşı ile tüm toplum aşılanana kadar yapılması önerilmektedir. Sitomegalovirüs, hepatit C Virüsü ve HIV açısından taramanın ise yalnızca riskli gruplarla sınırlandırılması uygun görülmektedir.Anahtar kelimeler: Toksoplazma, rubella, sitomegalovirüs, prevalans, gebelik ABSTRACT Objective: Primary infections caused by rubella, cytomegalovirus, toxoplasma can lead to serious complications in pregnancy. The aim of our study is to determine the prevalence of rubella, cytomegalovirus, toxoplasma, Hepatitis B virus, Hepatitis C virus, HIV among pregnant women. Methods: The study was carried out in Muğla Sıtkı Koçman University Faculty of Medicine, Department of Obstetrics and Gynecology between June 2014-February 2015. Pregnant women aged 18-44 years who consulted to Clinics of Ryn&Obs were evaluated as for toxoplasmosis, (n=191), rubella (n= 189), cytomegalovirus infection (n=136), and hepatitis and HIV (n=133) were enrolled in this study. The results of the serological screening tests performed during the first trimester of pregnancy were evaluated. Results: Anti-IgG against rubella was found in 170 (89.5%) and rubella IgM in one pregnant woman (0.8%). The positivity for anti-cytomegalovirus IgG, and anti-cytomegalovirus IgM antibody were found in 123 (90.4%), and 1 (0.3%) women, respectively. Anti-IgG against toxoplasma was found in 36 women (18.8%) and toxoplasma IgM in 7 women (3.7%). The positivity for HbsAg was found in 5 women (1.8%), while 78 women (23.7%) were positive for the anti-HbS. The seropositivity for anti hepatitis C virus antibody was found in 1 (0.3%) woman. In any women anti HIV positivity was not detected. Conclusion: Treatment of toxoplazmosis in the fetus and infant during the first year of life has been known to improve the outcome. Serological screening of toxoplasmosis in pregnant women is the most reliable and currently available strategy for the prevention, diagnosis, and early treatment of the infection in the offspring. Screening for rubella should be performed before pregnancy and vaccination should be advised for seronegative females. HBsAg screening should be recommended until whole society is vaccinated. Limiting screening for vcytomegalovirus, hepatitis C virus and HIV for risky grou...

The aim of this study was to determine the prognostic role of echocardiography and compare with admission N-terminal proB-type natriuretic peptide (NT-proBNP) levels in adult patients with community-acquired pneumonia (CAP). Consecutive adult patients hospitalized with CAP were prospectively enrolled and followed-up until hospital discharge or death. Echocardiography was performed within the first 48 hours. Complicated hospitalization (CH) was defined as intensive care unit admission, need for mechanical ventilation or in-hospital mortality. This study was registered with ClinicalTrials.gov, number NCT02441855. A total of 15 CH (13.5%) occurred among 111 patients with CAP. CAP patients with a CH compared with those without CH had significantly higher NT-proBNP values (1267.4±1146.1 vs. 305.6±545.7 pg/mL, p <0.001) and troponin I (23.8±24.3 vs. 10.3±6.3 ng/mL, p 0.02) but had lower left ventricle ejection fraction (52.7±8.7 vs. 60.5±6.7%, p <0.001) and tricuspid annular plane systolic excursion (TAPSE), which is a measure of right ventricular systolic function (17.1±4.4 vs. 21.8±4 mm; p 0.001). Patients with elevation of NT-proBNP and decreased TAPSE at presentation had a significantly higher probability of CH (60%) than patients with either elevated NT-proBNP or decreased TAPSE (40%). Patients with neither elevated NT-proBNP nor decreased TAPSE had a 0% probability of CH. This is the first study to demonstrate that decreased right ventricular systolic function is associated with increased rates of adverse events in patients with CAP.

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