Introduction: Compulsory electromyoneurography (EMNG) analysis of all neurophysiological parameters, including the most sensitive parameter for early detection of diabetic polyneuropathy (cutaneous silent periods), in patients without subjective symptoms, and EMNG analysis demonstrates the existence of incipient signs for polynomial neuropathy due to which timely therapeutic approach is needed to prevent complications of diabetic disease and prevent irreversible changes in peripheral nerves. Aim: Examine the influence of type diabetes mellitus, therapeutic modality, and gender of patients on neurophysiological parameters obtained by EMNG analysis. Methods: The study included 90 patients with diabetes who were divided into three groups of 30, depending on the duration of the disease. Group 1 consisted of 30 respondents with type 2 diabetes mellitus and up to 5 years of disease duration. Group 2 consisted of 30 respondents with type 2 diabetes mellitus type and 5 to 10 years of disease duration. Group 3 consisted of 30 respondents with Type 1 diabetes mellitus. An electron-neurography analysis of peripheral nerve in the extremities was performed. Results: Group 1 (50%) and group 2 (56.17%) respondents had statistically higher incidence of tingling than those in Group 3 (13.3%), p=0.004. Tingling was not statistically significantly different in relation to the examined groups (p=0.314). Reflexes were statistically the most preserved in Group 3 (86.7%), p = 0.001. Measurement of motor conductivity values at median nerve had a significant difference in all parameters (distal latency, amplitude, mean conduction velocity (MCV) and latency in the group with DM type 1, compared to respondents with DM type 2. The same significant difference between all parameters was found when testing peroneus nerve. When measuring motor velocity conductivity in ulnar nerve, there was no significant difference in amplitude, while DM1 type 1 patients had significant differences in values: distal latency and MCV p<0.0001, latency p<0.002. Measurement of sensory velocity was not statistically significant between patients with DM types 1 and 2. In relation to therapy, oral insulin therapy was not shown to be of statistical significance, except for tibialis amplitude measurements, where insulin-treated DM patients had a value amplitude of 12.96±1.48, and in oral therapy group less than 0.04 (p<0.05) 9.14±0.93. In the DM type 2 group no, neurophysiological parameters showed significant gender differences, while in respondents with DM type 2, where the disease lasted shorter, a significant gender difference was present in terms of motor velocity and sensory conductivity in all the nerves examines, except MCV in ulnar nerve. In the DM type 1 respondents, a significant gender difference was present in measuring MCV at tibial nerve and peroneus nerve (p <0.01 and p <0.02), as well as latency of MCV in H reflexes (p<0.01), in males was 56.25±1.03...

Aim:To examine the morphologic variations of occipital sulci patterns in patients with schizophrenia and migraine haeadache regarding gender and laterality as well as damage of visual pathway in patients with schizophrenia using magnetic resonance imagining (MRI) and visual evoked potentials (VEPs).Methods:This study included 80 patients and brain scans and visual evoked potential responses recorded over the occipital cortex were performed to analyze the occipital region of both hemispheres. Average total volumes of both hemispheres and average values of amplitude of the healthy population for the comparasion were used.Results:There was statistically significant difference between subjects considering gender (p=0.012). Parameters of parieto-occipital fissure (p=0.0314) showed statistically significant positive correlation with P100 amplitude (p=0.05), body of the calcarine sulcus (p=0.0213) had significant positive correlation with P100 amplitude (p=0.04), retro calcarine sulcus (p=0.0516) and P100 amplitude (p=0.03) showed statistically significant difference only of left hemisphere in male patients with schizophrenia with shallower depth of the sulcus and P100 amplitude reduction.Conclusion:Schizophrenia is associated with the volume changes of the occipital lobe. Comparative analysis of morphologic differences in the gray matter of occipital lobe using MRI and VEPs revealed changes especially of the left hemisphere (shallower depth of sulcus and P100 amplitude reduction) only among a group of male patients.

Introduction:Neurophysiological tests allow accurate assessment of the function of the peripheral nervous system. Detection of neurophysiological changes allows us to understand the neurological clinical symptoms and signs of patients with type 1 and type 2 diabetes and the possibility for their symptomatic treatment.Aim:Evaluate the effect of diabetes mellitus on the “cutaneous silent period” in detecting diabetic polyneuropathy.Material and Methods:The study included 150 subjects, 90 suffering from diabetes, divided into three groups of 30, depending on the disease duration, and a control group of 60 respondents not suffering from diabetes or other polyneuropathies. The control group are referred for EMG analysis on another basis (cervical radiculopathy, brachialgia, etc.). Group 1 consisted of 30 subjects with diabetes mellitus type 2 and duration of illness up to 5 years. Group 2 consisted of 30 subjects with type 2 diabetes mellitus 2 and illness duration from 5 to 10 years. Group 3 consisted of 30 patients with type 1 diabetes mellitus. The study groups consisted of patients referred for EMNG analysis to the EMG office of the Clinical Center of Sarajevo University, Neurology Clinic and the Neurophysiology Laboratory in Ljubljana, from July 1, 2011 to May 1, 2016. All patients were examined neurologically and electroneurographic analysis was performed.Results:A statistically significant difference was found in the incidence of pathologic CSP with respect to the study groups, χ2 = 26.153; p=0.001. Pathologic CSP was more common in group 1 and group 2 of subjects (56.17%) compared to group 3 and control subjects, where it occurred in 13.3% of the cases.Conclusion:The pathological cutaneous period of silence was more frequent in subjects of group 1 and group 2, that is, in subjects with DM type 2, compared to subjects with DM type 1.

Aim To compare morphologic variations of occipital sulci patterns in patients with schizophrenia and migraine headache regarding gender and laterality using magnetic resonance imaging (MRI) and visual evoked potentials (VEPs) as well as damage of visual pathway in patients with schizophrenia.